Oxytocin and addiction: a review
Neuropeptides affect adaptive central nervous system processes related to opiate ethanol
and cocaine addiction. Oxytocin (OXT), a neurohypophyseal neuropeptide synthesized in …
and cocaine addiction. Oxytocin (OXT), a neurohypophyseal neuropeptide synthesized in …
Role of oxytocin in the neuroadaptation to drugs of abuse
Oxytocin (OXT), a neurohypophyseal hormone, has a wide range of behavioral effects
outside its classic peripheral endocrine functions. OXT involvement in adaptive central …
outside its classic peripheral endocrine functions. OXT involvement in adaptive central …
Targeting the oxytocin system to treat addictive disorders: rationale and progress to date
The neuropeptide oxytocin plays a role in reward, stress, social affiliation, learning, and
memory processes. As such, there is increasing interest in oxytocin as a potential treatment …
memory processes. As such, there is increasing interest in oxytocin as a potential treatment …
The role of oxytocin in alcohol and drug abuse
The neuropeptide oxytocin (OXT) plays a key role in adaptive processes associated with
reward, tolerance, memory and stress responses. Through interactions with brain reward …
reward, tolerance, memory and stress responses. Through interactions with brain reward …
Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in …
Recent preclinical evidence indicates that the neuropeptide oxytocin may have potential in
the treatment of drug dependence and drug withdrawal. Oxytocin reduces …
the treatment of drug dependence and drug withdrawal. Oxytocin reduces …
A brief history of oxytocin and its role in modulating psychostimulant effects
DS Carson, AJ Guastella, ER Taylor… - Journal of …, 2013 - journals.sagepub.com
Over the past century, the polypeptide oxytocin has played an important role in medicine
with major highlights including the identification of its involvement in parturition and the milk …
with major highlights including the identification of its involvement in parturition and the milk …
Inhibition by oxytocin of methamphetamine-induced hyperactivity related to dopamine turnover in the mesolimbic region in mice
J Qi, JY Yang, M Song, Y Li, F Wang, CF Wu - … -Schmiedeberg's archives of …, 2008 - Springer
Accumulated data have shown the neuroactive properties of oxytocin (OT), a
neurohypophyseal neuropeptide, and its capability of reducing the abuse potential of drugs …
neurohypophyseal neuropeptide, and its capability of reducing the abuse potential of drugs …
The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice
P Zanos, P Georgiou, SR Wright, SM Hourani… - …, 2014 - nature.com
The main challenge in treating opioid addicts is to maintain abstinence due to the affective
consequences associated with withdrawal which may trigger relapse. Emerging evidence …
consequences associated with withdrawal which may trigger relapse. Emerging evidence …
Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats
There is emerging evidence that the neuropeptide oxytocin may be utilised as a treatment
for various psychopathologies, including drug addictions. Here we used an animal model to …
for various psychopathologies, including drug addictions. Here we used an animal model to …
Oxytocin for the treatment of drug and alcohol use disorders
MR Lee, EM Weerts - Behavioural pharmacology, 2016 - journals.lww.com
There is growing interest in the use of oxytocin (OT) as a potential treatment for alcohol and
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …
other substance-use disorders. OT is a neuropeptide that modulates adaptive processes …