Food digestion requires the cooperation of different digestive organs. The differentiation of
digestive organs is crucial for larvae to start feeding. Therefore, during digestive …

Intestinal tumorigenesis is a result of mutations in signaling pathways that control cellular
proliferation, differentiation, and survival. Mutations in the Wnt/β-catenin pathway are …

Gastric cancer (GC) is the fourth common cancer and second leading cause of cancer‐
related mortality in the world. WD repeat domain 5 (WDR5) has been identified that its …

Homeostasis and maturation of the mammalian intestinal epithelium are preserved through
strict regulation of cell proliferation, apoptosis, and differentiation, but the exact mechanism …

Definitive endoderm differentiation is crucial for generating respiratory and gastrointestinal
organs including pancreas and liver. However, whether epigenetic regulation contributes to …

Objectives N6-methyladenosine (m6A) RNA methylation is implicated in the progression of
multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in …

Colorectal cancer (CRC) is the third most common cause of cancer deaths, and has a high
rate of liver and lung metastasis. Unfortunately, distant metastasis is the main barrier for …

Abstract N6‐methyladenosine (m6A) mRNA methylation has emerged as an important
player in many biological processes by regulating gene expression. However, its roles in …

The M2 isoform of pyruvate kinase (PKM2) is abundantly expressed in various cancer cells
and associated with tumorigenesis, tumour proliferation and tumour progression. However …

USP21 is a kind of deubiquitinating enzymes involved in the malignant progression of
various cancers, while its role in gastric cancer (GC) and the specific molecular mechanism …