Prospective study of neuropeptide y as an adverse cardiovascular risk factor in end-stage renal disease

C Zoccali, F Mallamaci, G Tripepi… - Journal of the …, 2003 - journals.lww.com
Chronic renal insufficiency is a situation characterized by high plasma concentration of
neuropeptide Y (NPY). Because this neuropeptide interferes with cardiovascular (CV) …

Neuropeptide Y predicts cardiovascular events in chronic kidney disease patients: a cohort study

C Zoccali, G D'Arrigo, D Leonardis, P Pizzini… - Journal of …, 2019 - journals.lww.com
Background: Neuropeptide Y (NPY) is a multifaceted sympathetic neurotransmitter
regulating reflex cardiovascular control, myocardial cell growth, inflammation and innate …

Neuropeptide Y and chronic kidney disease progression: a cohort study

C Zoccali, G D'arrigo, D Leonardis… - Nephrology Dialysis …, 2018 - academic.oup.com
ABSTRACT Background Neuropeptide Y (NPY) is a sympathetic neurotransmitter that has
been implicated in various disorders including obesity, gastrointestinal and cardiovascular …

Elevated plasma concentrations of neuropeptide Y in children and adults with chronic and terminal renal failure

M Bald, M Gerigk, W Rascher - American journal of kidney diseases, 1997 - Elsevier
Neuropeptide Y (NPY) is a peptide hormone that is expressed, stored, and released in
sympathetic neurones together with noradrenaline. Elevated plasma concentrations of NPY …

Is neuropeptide Y a contributor to volume-induced hypertension?

I Odar-Cederlof, F Ericsson, E Theodorsson… - American journal of …, 1998 - Elsevier
Hypertension often occurs with fluid overload. The most common mechanism is considered
to be mediated by increased cardiac output. Hemodialysis (HD) patients frequently have …

Neuropeptide Y is elevated in heart failure and is an independent predictor of outcomes

K McDowell, C Adamson, C Jackson… - European Journal of …, 2024 - Wiley Online Library
Abstract Aims Neuropeptide Y (NPY) is the most abundant neuropeptide found in the heart
and is released alongside norepinephrine following prolonged sympathetic activation, a …

Increased plasma immunoreactive neuropeptide Y concentrations in phaeochromocytoma and chronic renal failure

K Takahashi, T Mouri, K Itoi, M Sone… - Journal of …, 1987 - journals.lww.com
To investigate the clinical usefulness of radio-immunoassay of neuropeptide Y (NPY), we
measured plasma immunoreactive neuropeptide Y (IR-NPY) concentrations in normal …

Neuropeptide Y as a risk factor for cardiorenal disease and cognitive dysfunction in chronic kidney disease: translational opportunities and challenges

C Zoccali, A Ortiz, IA Blumbyte, S Rudolf… - Nephrology Dialysis …, 2022 - academic.oup.com
Neuropeptide Y (NPY) is a 36-amino-acid peptide member of a family also including peptide
YY and pancreatic polypeptide, which are all ligands to Gi/Go coupled receptors. NPY …

Neuropeptide Y, left ventricular mass and function in patients with end stage renal disease

C Zoccali, F Mallamaci, G Tripepi… - Journal of …, 2003 - journals.lww.com
Objective Neuropeptide Y (NPY) is released during sympathetic stimulation and mediates
the central effects of the adipostatic hormone leptin. The plasma concentration of NPY and …

Circulating neuropeptide Y in plasma from uremic patients consists of multiple peptide fragments

J Hegbrant, H Thysell, R Ekman - Peptides, 1995 - Elsevier
Increased plasma levels of neuropeptide Y (NPY)-like immunoreactivity (p-NPY-LI) have
been described in hemodialysis (HD) patients. In this investigation the effect of a standard …