ONS-donor ligand based Pt (II) complexes display extremely high anticancer potency through autophagic cell death pathway

FU Rahman, A Ali, HQ Duong, IU Khan… - European Journal of …, 2019 - Elsevier
The current study unveils ONS-donor ligand based Pt (II) complexes with unusual anticancer
potency showing higher anticancer effect as compared to cisplatin. This series of Pt (II)(R …

Novel Pt(ii) complexes with modified aroyl-hydrazone Schiff-base ligands: synthesis, cytotoxicity and action mechanism

J Deng, P Yu, Z Zhang, J Zhang, S Zhewen, M Cai… - Metallomics, 2019 - academic.oup.com
To develop new anti-tumour Pt (ii) agents, we designed and synthesized five Pt (ii)
complexes. These Pt (ii) complexes were modified benzene rings of 2-hydroxybenzylidene …

Structure and biological properties of five Pt (II) complexes as potential anticancer agents

J Deng, J Wang, MH Khan, P Yu, F Yang… - Journal of inorganic …, 2018 - Elsevier
We synthesized and validated five Schiff base Pt (II) complexes derived from 2-hydroxy-1-
naphthaldehyde benzoyl hydrazone and its derivatives, which are modified at the …

Exploring heterometallic bridged Pt (II)-Zn (II) complexes as potential antitumor agents

TV Soldatović, B Šmit, EM Mrkalić, SL Matić… - Journal of inorganic …, 2023 - Elsevier
The four novel complexes [{cis-PtCl (NH 3) 2 (μ-4, 4′-bipyridyl) ZnCl (terpy)}](ClO 4) 2
(C1),[{trans-PtCl (NH 3) 2 (μ-4, 4′-bipyridyl) ZnCl (terpy)}](ClO 4) 2 (C2),[{cis-PtCl (NH 3) 2 …

Platinum (II) 5-substituted-8-hydroxyquinoline coordination compounds induces mitophagy-mediated apoptosis in A549/DDP cancer cells

Y Yang, LQ Du, Y Huang, CJ Liang, QP Qin… - Journal of Inorganic …, 2023 - Elsevier
For the first time, two new mononuclear platinum (II) coordination compounds,[Pt
(L1)(DMSO) Cl](PtL1) and [Pt (L2)(DMSO) Cl](PtL2) with the 5-(ethoxymethyl)-8 …

Highly promising antitumor agent of a novel Platinum (II) complex bearing a tetradentate chelating ligand

I Yılmaz, OR Akar, M Erkisa, S Selvi… - ACS Medicinal …, 2020 - ACS Publications
A new mononuclear cationic platinum (II) coordination compound with 6, 6′-bis (NH-
benzimidazol-2-yl)-2, 2′-bipyridine (L) ligand having N4-tetradentate binding pocket [Pt (L)] …

Synthesis and anticancer activities of a novel class of mono-and di-metallic Pt (II)(salicylaldiminato)(DMSO or Picolino) Cl complexes

FU Rahman, A Ali, R Guo, YC Zhang, H Wang… - Dalton …, 2015 - pubs.rsc.org
A series of novel Pt (II) complexes [cis-and trans-Pt (II)(salicylaldimine)(DMSO) Cl (C-1),
trans-Pt (II)(salicylaldimine)(4-picoline) Cl (C-2), Pt (II)(salicylaldimine) Cl (C-3), trans-and …

[HTML][HTML] Tuning the anticancer properties of Pt (II) complexes via structurally flexible N-(2-picolyl) salicylimine ligands

KS Al-Rashdi, BA Babgi, EMM Ali, B Davaasuren… - RSC …, 2022 - pubs.rsc.org
Three tridentate Schiff base ligands were synthesized from the reactions between 2-
picolylamine and salicylaldehyde derivatives (3-ethoxy (OEt), 4-diethylamino (NEt2) and 4 …

Investigation of effects of newly synthesized Pt (II) complex against human serum albumin and leukemia cell line of K562

A Divsalar, AA Saboury, L Ahadi, E Zemanatiyar… - BMB …, 2010 - koreascience.kr
The biological evaluation of a new synthesized Pt (II)-complex, 2, 2'-bipyridin Butylglycinato
Pt (II) nitrate, an anti-tumor component, was studied at different temperatures by …

Platinum (II) Complexes with 1, 10‐Phenanthroline and Hydrophilic Alkoxyacetate Ligands as Potential Antitumor Agents

Y Sun, H Wei, Q Zhang, X Zhao - Chemistry & Biodiversity, 2019 - Wiley Online Library
Four platinum complexes, formulated as [Pt (phen)(OCOCH2OR) 2](phen= 1, 10‐
phenanthroline, R= Me, Et, iPr, or tBu), have been synthesized and well characterized by …