Immune checkpoint blockade in patients with triple-negative breast cancer

LL Michel, A von Au, A Mavratzas, K Smetanay… - Targeted Oncology, 2020 - Springer
Triple-negative breast cancer constitutes~ 15% of all breast cancer subtypes. Because of the
negative hormone receptor and human epidermal growth factor receptor 2 status, therapy is …

Navigating practical challenges in immunotherapy for metastatic triple negative breast cancer

L Licata, MV Dieci, C De Angelis, C Marchiò… - Cancer Treatment …, 2024 - Elsevier
Immunotherapy has revolutionized cancer therapy and now represents a standard of care
for many tumor types, including triple-negative breast cancer. Despite the positive results …

Current state of knowledge on the immune checkpoint inhibitors in triple-negative breast cancer treatment: approaches, efficacy, and challenges

K Uchimiak… - Clinical Medicine …, 2022 - journals.sagepub.com
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with
limited treatment options. Recently, there has been a growing interest in immunotherapy …

[HTML][HTML] Immunotherapy treatment for triple negative breast cancer

ER Berger, T Park, A Saridakis, M Golshan… - Pharmaceuticals, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes of
breast cancer and has dismal prognosis. Local recurrence rate after standard therapy in the …

Immune checkpoint inhibitors in triple negative breast cancer: the search for the optimal biomarker

S Qureshi, N Chan, M George, S Ganesan… - Biomarker …, 2022 - journals.sagepub.com
Triple negative breast cancer (TNBC) is a high-risk and aggressive malignancy
characterized by the absence of estrogen receptors (ER) and progesterone receptors (PR) …

Immune checkpoint inhibition in early-stage triple-negative breast cancer

R Varma, M Wright, J Abraham… - Expert review of …, 2022 - Taylor & Francis
Introduction Breast cancer cells can evade immune recognition by upregulating
programmed death-ligand 1 (PD-L1) leading to decreased T cell function. Anti-PD-1 agents …

[HTML][HTML] Checkpoint inhibitor therapy for metastatic triple-negative breast cancer

AL Heeke, AR Tan - Cancer and Metastasis Reviews, 2021 - Springer
Immunotherapy has become a mainstay of cancer treatment in many malignancies, though
its application in breast cancer remains limited. Of the breast cancer subtypes, triple …

Emerging strategies for TNBC with early clinical data: New chemoimmunotherapy strategies

PE Hall, P Schmid - Breast Cancer Research and Treatment, 2022 - Springer
Purpose The use of immune checkpoint inhibitors in combination with chemotherapy for the
treatment of triple-negative breast cancer is becoming more widespread as efficacy data …

Progress in immune checkpoint inhibition in early-stage triple-negative breast cancer

A Mohamed, M Kruse, J Tran - Expert Review of Anticancer …, 2023 - Taylor & Francis
Introduction Immune checkpoint inhibitors have been particularly effective in treating
cancers with robust immune microenvironments and have been successfully incorporated …

[HTML][HTML] Hope and hype around immunotherapy in triple-negative breast cancer

F Jacobs, E Agostinetto, C Miggiano, R De Sanctis… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is the most aggressive breast cancer
subtype accounting for approximately 10–20% of all cases. Due to a lack of actionable …