Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-α antibody
R Malaviya, A Bellomo, E Abramova… - Toxicology and applied …, 2021 - Elsevier
Sulfur mustard (SM) is a bifunctional alkylating agent that causes severe injury to the
respiratory tract. This is accompanied by an accumulation of macrophages in the lung and …
respiratory tract. This is accompanied by an accumulation of macrophages in the lung and …
Inflammatory effects of inhaled sulfur mustard in rat lung
R Malaviya, VR Sunil, J Cervelli, DR Anderson… - Toxicology and applied …, 2010 - Elsevier
Inhalation of sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung
damage, is a significant threat to both military and civilian populations. The mechanisms …
damage, is a significant threat to both military and civilian populations. The mechanisms …
Mechanism underlying acute lung injury due to sulfur mustard exposure in rats
Z Xiaoji, M Xiao, X Rui, C Haibo… - Toxicology and …, 2016 - journals.sagepub.com
Sulfur mustard (SM), a bifunctional alkylating agent that causes severe lung damage, is a
significant threat to both military and civilian populations. The mechanisms mediating the …
significant threat to both military and civilian populations. The mechanisms mediating the …
Progressive lung injury, inflammation, and fibrosis in rats following inhalation of sulfur mustard
R Malaviya, EV Abramova, RC Rancourt… - Toxicological …, 2020 - academic.oup.com
Sulfur mustard (SM) inhalation causes debilitating pulmonary injury in humans which
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …
progresses to fibrosis. Herein, we developed a rat model of SM toxicity which parallels …
Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicity
Sulfur mustard (SM) is highly toxic to the lung inducing both acute and chronic effects
including upper and lower obstructive disease, airway inflammation, and acute respiratory …
including upper and lower obstructive disease, airway inflammation, and acute respiratory …
Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury
DR Anderson, SL Taylor, DP Fetterer, WW Holmes - Toxicology, 2009 - Elsevier
Sulfur mustard (SM)-induced lung injury has been associated with protease activation,
oxidative injury and inflammatory response culminating in tissue necrosis. The protease …
oxidative injury and inflammatory response culminating in tissue necrosis. The protease …
A review of sulfur mustard-induced pulmonary Immunopathology: an alveolar macrophage approach
Despite many studies investigating the mechanism of Sulfur Mustard (SM) induced lung
injury, the underlying mechanism is still unclear. Inflammatory and subsequent …
injury, the underlying mechanism is still unclear. Inflammatory and subsequent …
In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and …
D Yu, Y Bei, Y Li, W Han, Y Zhong, F Liu, Y Zhao… - International …, 2017 - Elsevier
This study was to investigate the differences of inflammatory reaction and oxidative stress
due to sulfur mustard (SM)-induced acute pulmonary injury via two ways in rats. In …
due to sulfur mustard (SM)-induced acute pulmonary injury via two ways in rats. In …
Sulfur mustard inhalation induced respiratory lesions in guinea pigs: Physiological, biochemical, and histological study
N Allon, E Gilat, A Amir, E Fishbine, H Liani - 1993 - osti.gov
Inhalation exposure to sulfur mustard (SM) vapor causes long term damage to the
respiratory system. The lesions were characterized by specific physiological, biochemical …
respiratory system. The lesions were characterized by specific physiological, biochemical …
Role of oxidative stress in sulfur mustard-induced pulmonary injury and antioxidant protection
E Tahmasbpour, S Reza Emami, M Ghanei… - Inhalation …, 2015 - Taylor & Francis
Sulfur mustard (SM) is a potent alkylating agent that targets several organs, especially lung
tissue. Although pathological effects of SM have been widely considered, molecular and …
tissue. Although pathological effects of SM have been widely considered, molecular and …
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