The carotid body (CB) is the main peripheral chemoreceptor that senses the arterial PO 2,
PCO 2 and pH. In response to hypoxemia, hypercapnia and acidosis, carotid chemosensory …

We assessed the speed of the ventilatory response to square-wave changes in alveolar
Pco2 and the relative gains of the steady-state ventilatory response to CO2 of the central …

To some it may seem that we now know less about respiratory chemoreception than we did
20 years ago. Back then, it was widely accepted that the central respiratory chemoreceptors …

Animal respiration is the process by which oxygen (0,) is delivered to the cells to oxidize
nutrients and obtain the energy necessary for all vital functions; carbon dioxide (CO,) is …

A diverse group of processes are involved in central control of ventilation. Both fast acting
neurotransmitters and slower acting neuromodulators are involved in the central respiratory …

This paper uses a steady-state modeling approach to describe the effects of changes in acid-
base balance on the chemoreflex control of breathing. First, a mathematical model is …

Acid-sensitive K+ channels of the tandem P-domain K+-channel family (TASK-1 and TASK-
3) have been implicated in peripheral and central respiratory chemosensitivity; however …

The rat retrotrapezoid nucleus (RTN) contains neurons described as central chemoreceptors
in the adult and respiratory rhythm-generating pacemakers in neonates [parafacial …

Sympathetic nerve activity (SNA) is modulated by respiratory activity which indicates the
existence of direct interactions between the respiratory and sympathetic networks within the …

Peripheral chemoreceptors (carotid and aortic bodies) detect changes in arterial blood
oxygen and initiate reflexes that are important for maintaining homeostasis during …