Central sleep apnoea (CSA)–the temporary absence or diminution of ventilatory effort during
sleep–is seen in a variety of forms including periodic breathing in infancy and healthy adults …

Adjustments of respiration and circulation in response to alterations in the levels of oxygen,
carbon dioxide and hydrogen ions in the body fluids are mediated by two distinct …

Hypertension elicited by chronic intermittent hypoxia (CIH) is associated with elevated
activity of the thoracic sympathetic nerve (tSN) that exhibits an enhanced respiratory …

The adaptation to hypoxia and hypercapnia requires the activation of several anatomical
structures along the neuraxis. In this study, using Fos immunoreactivity, we sought to map …

Peripheral and central chemoreflexes are the dominant autonomic mechanisms regulating
ventilatory patterns in response to changes in partial pressures of oxygen and carbon …

Much of biology is rhythmical and comprises oscillators that can couple. These have
optimized energy efficiency and have been preserved during evolution. The respiratory and …

Brain stem muscarinic cholinergic pathways are important in respiratory carbon dioxide
(CO2) chemosensitivity. Defects in the muscarinic system have been reported in children …

The chemoreflexes are important modulators of sympathetic activation. The peripheral
chemoreceptors located in the carotid bodies respond primarily to hypoxaemia. Central …