Metabolome analysis using capillary electrophoresis (CE) coupled with high-resolution
mass spectrometry (HRMS) has the potential to improve coverage of metabolite detection …

Sample preparation remains a challenge in untargeted metabolomics studies and no
method currently results in complete extraction of all metabolite classes in human plasma …

Capillary electrophoresis-mass spectrometry (CE-MS) has emerged as a powerful new tool
for comprehensive analysis of charged compounds. In this review, we provide a general …

Highlights•CE–MS is an attractive analytical tool for analyzing the polar ionogenic
metabolome.•A novel sheathless interface for CE–MS allows highly sensitive metabolic …

Metabolomics is the study of small molecules, primarily metabolites, that are produced
during metabolic processes. Analysis of the composition of an organism's metabolome can …

Capillary electrophoresis mass spectrometry (CE-MS) is now regarded as a powerful tool for
the comprehensive analysis of low-molecular-weight charged metabolites. Over the past …

In metabolomics, a large number of small molecules can be detected in a single run.
However, metabolomic data do not include the absolute concentrations of each metabolite …

This work aims at evaluating the relevance and versatility of liquid chromatography coupled
to high resolution mass spectrometry (LC/HRMS) for performing a qualitative and …

Capillary electrophoresis coupled to mass spectrometry is a power tool in untargeted
metabolomics studies to analyze charged and polar compounds. However, identification is a …

Recently, the use of metabolomic analysis of human serum and plasma for biomarker
discovery and disease diagnosis in clinical studies has been increasing. The feasibility of …