Background: The relationship between cerebral small vessel disease (SVD) and dementia
has been studied without considering white matter (WM) volume, the microstructural integrity …

Objective: Cerebral small vessel disease (SVD) is considered the most important vascular
contributor to cognitive decline and dementia, although a causal relation between its MRI …

Importance It remains unclear if and how associations between cerebral small-vessel
disease and Alzheimer disease (AD) pathology lead to cognitive decline and dementia …

Background: Recent evidence suggests that combining individual imaging markers of
cerebral small vessel disease (SVD) may more accurately reflect its overall burden and …

Introduction It is unknown whether different types of small vessel disease (SVD),
differentially relate to brain atrophy and if co‐occurring Alzheimer's disease pathology …

Introduction Cerebral small vessel disease is increasingly linked to dementia. Methods We
systematically searched Medline, Embase, and Cochrane databases for prospective …

White matter hyperintensities (WMH) constitute the visible spectrum of cerebral small vessel
disease (SVD) markers and are associated with cognitive decline, although they do not fully …

Background Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans
of elderly people and is related to vascular risk factors and cognitive and motor impairment …

Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …

Background and purpose Whilst there is evidence implicating small vessel cerebrovascular
disease in the pathogenesis of Alzheimer's disease (AD), its specific contribution to the …