Building a 5-HT3A receptor expression map in the mouse brain

Y Koyama, M Kondo, S Shimada - Scientific reports, 2017 - nature.com
Of the many serotonin receptors, the type 3 receptors (5-HT3R) are the only ionotropic ones,
playing a key role in fast synaptic transmission and cognitive and emotional brain function …

Htr2a Gene and 5-HT2A Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice

ET Weber, R Andrade - Frontiers in neuroscience, 2010 - frontiersin.org
Serotonin receptors of the 5-HT2A subtype are robustly expressed in the cerebral cortex
where they have been implicated in the pathophysiology and therapeutics of mental …

What Do We Really Know About 5-HT1A Receptor Signaling in Neuronal Cells?

PS Rojas, JL Fiedler - Frontiers in cellular neuroscience, 2016 - frontiersin.org
Serotonin (5-HT) is a neurotransmitter that plays an important role in neuronal plasticity.
Variations in the levels of 5-HT at the synaptic cleft, expression or dysfunction of 5-HT …

Expression of 5-HT7 receptor mRNA in rat brain during postnatal development

ML Vizuete, JL Venero, E Traiffort, C Vargas… - Neuroscience …, 1997 - Elsevier
The present study is the first one to demonstrate the expression of 5-HT7 receptor mRNA by
in situ hybridization during postnatal development. No quantitative developmental changes …

Role of the 5-HT7 receptor in the central nervous system: from current status to future perspectives

A Matthys, G Haegeman, K Van Craenenbroeck… - Molecular …, 2011 - Springer
Pharmacological and genetic tools targeting the 5-hydroxytryptamine (5-HT) 7 receptor in
preclinical animal models have implicated this receptor in diverse (patho) physiological …

Cellular mechanisms of the 5-HT7 receptor-mediated signaling

D Guseva, A Wirth, E Ponimaskin - Frontiers in behavioral …, 2014 - frontiersin.org
Serotonin (5-hydroxytryptamine or 5-HT) is an important neurotransmitter regulating a wide
range of physiological and pathological functions via activation of heterogeneously …

Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR

AD Medhurst, F Lezoualc'h, R Fischmeister… - Molecular brain …, 2001 - Elsevier
5-HT4 receptors mediate several physiological effects of 5-HT, particularly in the central
nervous system (CNS), heart and gut. Recently, several C-terminal splice variants of the …

The serotonin 5-HT3 receptor: a novel neurodevelopmental target

M Engel, MP Smidt, JA Hooft - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Serotonin (5-hydroxytryptamine, 5-HT), next to being an important neurotransmitter, recently
gained attention as a key-regulator of pre-and postnatal development in the mammalian …

Overexpression of 5‐HT2C receptors in forebrain leads to elevated anxiety and hypoactivity

A Kimura, PL Stevenson, RN Carter… - European Journal of …, 2009 - Wiley Online Library
The 5‐HT2C receptor has been implicated in mood and eating disorders. In general, it is
accepted that 5‐HT2C receptor agonists increase anxiety behaviours and induce …

Distribution of serotonin receptor 5-HT6 mRNA in rat neuronal subpopulations: a double in situ hybridization study

L Helboe, J Egebjerg, IEM De Jong - Neuroscience, 2015 - Elsevier
Abstract The 5-HT 6 receptor (5-HT 6 R) is almost exclusively expressed in the brain and
has emerged as a promising target for cognitive disorders, including Alzheimer's disease. In …