5-Hydroxytryptamine (5-HT) neurons in the midbrain dorsal raphe nucleus (DRN) are
implicated in the drug treatment and pathophysiology of a wide variety of neuropsychiatric …

The characterization and anatomical distribution of 5-hydroxytryptamine (5-HT) 7 receptor
binding sites in brain tissue has been hampered by the lack of a specific radioligand. In the …

While homomers containing 5-HT 3A subunits form functional ligand-gated serotonin (5-HT)
receptors in heterologous expression systems (Jackson, MB, and Yakel, JL (1995) Annu …

Abstract Serotonin (5-hydroxytryptamine, 5-HT) is a unique neurotransmitter which can
regulate various biological processes by activating thirteen different receptors. These …

Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT3) receptor is the
only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT3A and 5 …

The 5-HT3 receptor is a ligand-gated ion channel expressed on interneurons throughout the
brain. So far, analysis of the 5-HT3A knockout mouse revealed changes in nociceptive …

Abstract Although null mutant ('knockout') mice have provided valuable animal models to
complement traditional approaches to psychopharmacology, such animals may also show …

The serotonin 3 (5-HT3) receptor is a ligand gated ion channel unlike the other 5-HT
receptors which are G protein coupled receptors. The functional 5-HT3 receptor forms a …

It was a great honour and pleasure for us to prepare this book entitled 5-HT2A Receptors in
the Central Nervous System. The serotonin 5-HT2A receptor, cloned in 1994, is principally …

One of the most recently identified serotonin (5-hydroxytryptamine (5-HT)) receptor subtypes
is the 5-HT 6 receptor. Although in-depth localization studies reveal an exclusive distribution …