One of the most recently identified serotonin (5-hydroxytryptamine (5-HT)) receptor subtypes
is the 5-HT 6 receptor. Although in-depth localization studies reveal an exclusive distribution …

We have isolated from a human genomic library the human 5-hydroxytryptamine 5-HT5A
and 5-HT5B genes. The human 5-HT5A gene encodes a protein with similar characteristics …

The 5-HT7 receptor is one of the several serotonin (5-HT) receptor subtypes that are
expressed in the dorsal raphe nucleus (DRN). Some earlier findings suggested that 5-HT7 …

The precise involvement of 5-ht5A, 5-ht5B, 5-ht6 and 5-HT7 receptors in the pleiotropic
actions of 5-HT remain incompletely known. To gain insights into their physiological function …

Background and purpose: Recent evidence suggests that 5‐HT2C receptor activation may
inhibit midbrain 5‐HT neurones by activating neighbouring GABA neurones. This hypothesis …

5-Hydroxytryptamine exerts modulatory physiological effects on both the central and
peripheral nervous systems by activation of discrete receptor families. 5-ht5A is among the …

Abstract The serotonin (5-HT) 6 receptor is a Gs-coupled receptor exclusively expressed in
the central nervous system. Highest receptor densities are found in brain regions implicated …

We studied expression of the 5-HT 1A receptor in cortical and limbic areas of the brain of the
tree shrew. In situ hybridization with a receptor-specific probe and immunocytochemistry …

The 5-ht5A receptor is enigmatic among 5-HT receptors since, although the human receptor
was cloned in 1994, until recently, very little has been learnt about the function of the …

Abstract Serotonin 6 receptor (5‐HT6R) is a promising target for a variety of human
diseases, such as Alzheimer's disease (AD) and schizophrenia. However, the detailed …