The 5‐HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans

ME Haahr, P Fisher, K Holst, K Madsen… - Human brain …, 2013 - Wiley Online Library
The cerebral serotonin (5‐HT) system is involved in cognitive functions such as memory and
learning and animal studies have repeatedly shown that stimulation of the 5‐HT type 4 …

5-HT3 receptors: a potential therapeutic target for epilepsy

H Zhao, Y Lin, S Chen, X Li… - Current …, 2018 - ingentaconnect.com
Background: Epilepsy is a syndrome of brain dysfunction caused by spontaneous, abnormal
discharge. Many anti-epileptic drugs have developed in past decades. 5-HT is an important …

Activation of 5-HT6 receptors inhibits corticostriatal glutamatergic transmission

A Tassone, G Madeo, T Schirinzi, D Vita, F Puglisi… - …, 2011 - Elsevier
We investigated the effect of 5-HT6 receptor subtype activation on glutamatergic
transmission by means of whole-cell patch-clamp electrophysiological recordings from …

The serotonin 5-HT7 receptors: two decades of research

E Gellynck, K Heyninck, KW Andressen… - Experimental brain …, 2013 - Springer
Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …

Radioligand binding analysis of knockout mice reveals 5-hydroxytryptamine7 receptor distribution and uncovers 8-hydroxy-2-(di-n-propylamino) tetralin interaction …

P Bonaventure, D Nepomuceno, L Hein, JG Sutcliffe… - Neuroscience, 2004 - Elsevier
In the present autoradiographic study, we took advantage of 5-hydroxytryptamine7 (5-HT7)
receptor knockout mice to analyze the brain distribution of 5-HT7 receptor binding sites …

Mice over-expressing the 5-HT1A receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT

B Bert, H Fink, H Hörtnagl, RW Veh, B Davies… - Behavioural brain …, 2006 - Elsevier
The serotonin 1A (5-HT1A) receptor is one of the best described receptor subtypes of the
serotonergic system. Due to the complex distribution pattern, the pre-and postsynaptic …

Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain—a combined in situ hybridisation/in vitro receptor autoradiographic …

DT Chalmers, SJ Watson - Brain research, 1991 - Elsevier
The present study examined the comparative distribution of 5-HT 1A receptor mRNA and 5-
HT 1A receptors in rat brain using a combination of in situ hybridisation histochemistry and …

[HTML][HTML] Review of antidepressants in clinic and active ingredients of traditional Chinese medicine targeting 5-HT1A receptors

L Wang, Y Zhang, X Du, T Ding, W Gong… - Biomedicine & …, 2019 - Elsevier
Serotonin, which also named as 5-hydroxytryptamine (5-HT), is a neurotransmitter, which
plays significant roles in a wide range of physiological and pathological processes …

Autoradiographic Localization of 5-HT1E and 5-HT1F Binding Sites in Rat Brain: Effect of Serotonergic Lesioning

A Fugelli, C Moret, G Fillion - Journal of Receptors and Signal …, 1997 - Taylor & Francis
carboxamidotryptamine (5-CT)-insensitive binding sites labelled by [3H] 5-
hydroxytryptamine (5-HT) in the presence of 100 nM 5-CT and 100 nM mesulergine, were …

SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] propanamide dihydrochloride), a novel 5-ht5A …

DR Thomas, EM Soffin, C Roberts, JNC Kew… - …, 2006 - Elsevier
This study utilised the selective 5-ht5A receptor antagonist, SB-699551-A (3-cyclopentyl-N-
[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] …