The 5‐HT4 receptor levels in hippocampus correlates inversely with memory test performance in humans
The cerebral serotonin (5‐HT) system is involved in cognitive functions such as memory and
learning and animal studies have repeatedly shown that stimulation of the 5‐HT type 4 …
learning and animal studies have repeatedly shown that stimulation of the 5‐HT type 4 …
5-HT3 receptors: a potential therapeutic target for epilepsy
H Zhao, Y Lin, S Chen, X Li… - Current …, 2018 - ingentaconnect.com
Background: Epilepsy is a syndrome of brain dysfunction caused by spontaneous, abnormal
discharge. Many anti-epileptic drugs have developed in past decades. 5-HT is an important …
discharge. Many anti-epileptic drugs have developed in past decades. 5-HT is an important …
Activation of 5-HT6 receptors inhibits corticostriatal glutamatergic transmission
We investigated the effect of 5-HT6 receptor subtype activation on glutamatergic
transmission by means of whole-cell patch-clamp electrophysiological recordings from …
transmission by means of whole-cell patch-clamp electrophysiological recordings from …
The serotonin 5-HT7 receptors: two decades of research
E Gellynck, K Heyninck, KW Andressen… - Experimental brain …, 2013 - Springer
Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …
pharmacological consequences are more complex and diverse. Serotonin is involved in …
Radioligand binding analysis of knockout mice reveals 5-hydroxytryptamine7 receptor distribution and uncovers 8-hydroxy-2-(di-n-propylamino) tetralin interaction …
P Bonaventure, D Nepomuceno, L Hein, JG Sutcliffe… - Neuroscience, 2004 - Elsevier
In the present autoradiographic study, we took advantage of 5-hydroxytryptamine7 (5-HT7)
receptor knockout mice to analyze the brain distribution of 5-HT7 receptor binding sites …
receptor knockout mice to analyze the brain distribution of 5-HT7 receptor binding sites …
Mice over-expressing the 5-HT1A receptor in cortex and dentate gyrus display exaggerated locomotor and hypothermic response to 8-OH-DPAT
B Bert, H Fink, H Hörtnagl, RW Veh, B Davies… - Behavioural brain …, 2006 - Elsevier
The serotonin 1A (5-HT1A) receptor is one of the best described receptor subtypes of the
serotonergic system. Due to the complex distribution pattern, the pre-and postsynaptic …
serotonergic system. Due to the complex distribution pattern, the pre-and postsynaptic …
Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain—a combined in situ hybridisation/in vitro receptor autoradiographic …
DT Chalmers, SJ Watson - Brain research, 1991 - Elsevier
The present study examined the comparative distribution of 5-HT 1A receptor mRNA and 5-
HT 1A receptors in rat brain using a combination of in situ hybridisation histochemistry and …
HT 1A receptors in rat brain using a combination of in situ hybridisation histochemistry and …
[HTML][HTML] Review of antidepressants in clinic and active ingredients of traditional Chinese medicine targeting 5-HT1A receptors
L Wang, Y Zhang, X Du, T Ding, W Gong… - Biomedicine & …, 2019 - Elsevier
Serotonin, which also named as 5-hydroxytryptamine (5-HT), is a neurotransmitter, which
plays significant roles in a wide range of physiological and pathological processes …
plays significant roles in a wide range of physiological and pathological processes …
Autoradiographic Localization of 5-HT1E and 5-HT1F Binding Sites in Rat Brain: Effect of Serotonergic Lesioning
A Fugelli, C Moret, G Fillion - Journal of Receptors and Signal …, 1997 - Taylor & Francis
carboxamidotryptamine (5-CT)-insensitive binding sites labelled by [3H] 5-
hydroxytryptamine (5-HT) in the presence of 100 nM 5-CT and 100 nM mesulergine, were …
hydroxytryptamine (5-HT) in the presence of 100 nM 5-CT and 100 nM mesulergine, were …
SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] propanamide dihydrochloride), a novel 5-ht5A …
DR Thomas, EM Soffin, C Roberts, JNC Kew… - …, 2006 - Elsevier
This study utilised the selective 5-ht5A receptor antagonist, SB-699551-A (3-cyclopentyl-N-
[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] …
[2-(dimethylamino) ethyl]-N-[(4′-{[(2-phenylethyl) amino] methyl}-4-biphenylyl) methyl] …