Reward systems and food intake: role of opioids

BA Gosnell, AS Levine - International journal of obesity, 2009 - nature.com
Humans eat for many reasons, including the rewarding qualities of foods. A host of
neurotransmitters have been shown to influence eating behavior and some of these appear …

Opioids as facilitators of feeding: can any food be rewarding?

PK Olszewski, J Alsiö, HB Schiöth, AS Levine - Physiology & behavior, 2011 - Elsevier
Palatability is one of the most rewarding aspects of consummatory behavior. Opioids, potent
facilitators of intake of sweet and fat tastants, are thought to mediate hedonics of feeding …

Opioids and food intake: distributed functional neural pathways?

MJ Glass, CJ Billington, AS Levine - Neuropeptides, 1999 - Elsevier
Agonists of the μ, δ, κ and ORL1opioid receptors increase food intake while opioid receptor
blockade decreases food intake. The majority of the collected data related to opioids and …

Central opioids and consumption of sweet tastants: when reward outweighs homeostasis

PK Olszewski, AS Levine - Physiology & behavior, 2007 - Elsevier
Numerous reports have described opioids as peptides involved in the regulation of food
intake. The role of these endogenous substances appears to be linked with reward …

Opioids as agents of reward-related feeding: a consideration of the evidence

AS Levine, CJ Billington - Physiology & behavior, 2004 - Elsevier
Gerard Smith was one of the pioneers in the field of neuropeptidergic control of food intake.
He established methodology and criteria used to determine whether a neuropeptide acts as …

The opioid system and food intake: homeostatic and hedonic mechanisms

R Nogueiras, A Romero-Picó, MJ Vazquez… - Obesity facts, 2012 - karger.com
Opioids are important in reward processes leading to addictive behavior such as self-
administration of opioids and other drugs of abuse including nicotine and alcohol. Opioids …

Opioids, feeding, and anorexias.

GK Yim, MT Lowy - Federation Proceedings, 1984 - europepmc.org
This review summarizes recent work that focuses on the role of endogenous opioids (EOs)
and opiate receptors in the control of food intake. Although the anorexic effect of opiate …

Which opioid receptor mechanism modulates feeding?

JE Morley, AS Levine, BA Gosnell, CJ Billington - Appetite, 1984 - Elsevier
There is substantial evidence for the role of endogenous opioid peptides in the regulation of
appetite. This communication examines the possible opioid peptide mechanism (s) which …

Preference or fat? Revisiting opioid effects on food intake

SA Taha - Physiology & behavior, 2010 - Elsevier
It is well established that opioid signaling in the central nervous system constitutes a
powerful stimulus for food intake. The role of opioids in determining food preference …

Food cravings, endogenous opioid peptides, and food intake: a review

ME Mercer, MD HOLDER - Appetite, 1997 - Elsevier
Extensive research indicates a strong relationship between endogenous opioid peptides
(EOPs) and food intake. In the present paper, we propose that food cravings act as an …