Publisher Summary This chapter discusses the status of the active Alzheimer's disease (AD)
therapeutic approaches as well as some areas that are only beginning to see medicinal …

Abstract Alzheimer's disease (AD), the most common form of dementia among the elderly, is
a progressive, degenerative disorder of the brain with a loss of memory and cognition. A …

Alzheimer's disease (AD) is the leading cause of dementia in mid-to-late life, and is
estimated to afflict approximately 20 million people worldwide. There are considerable …

Two main approaches can be adopted in the treatment of Alzheimer's disease (AD):
alleviation of cognitive deficits and/or slowing down neurodegenerative processes occurring …

Therapeutic research is being stepped up to light Alzheimer's disease (AD), although its
heterogeneity, the insufficiency of physiopathological knowledge, and the lack of a reference …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly (1). The
prevalence of AD at the age of 65 is approximately 10% and approaches 50% by the age of …

The endeavor to develop effective treatment of Alzheimer's disease (AD) has gained
momentum in the past few years. There is now a solid enough foundation of basic science …

Current treatment approaches in Alzheimer's disease are primarily symptomatic, with the
major therapeutic strategy based on acetylcho-linesterase inhibition. Alzheimer's disease …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by memory and
cognitive loss, and represents the leading cause of dementia in elderly people. Besides the …

Acetylcholine (ACh) has a crucial role in the peripheral and central nervous systems. The
enzyme choline acetyltransferase (ChAT) is responsible for synthesizing ACh from acetyl …