The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of β-site amyloid precursor …
WX Wang, BW Rajeev, AJ Stromberg… - Journal of …, 2008 - Soc Neuroscience
MicroRNAs (miRNAs) are small regulatory RNAs that participate in posttranscriptional gene
regulation in a sequence-specific manner. However, little is understood about the role (s) of …
regulation in a sequence-specific manner. However, little is understood about the role (s) of …
MiR-107 is reduced in Alzheimer's disease brain neocortex: validation study
MiR-107 is a microRNA (miRNA) that we reported previously to have decreased expression
in the temporal cortical gray matter early in the progression of Alzheimer's disease (AD) …
in the temporal cortical gray matter early in the progression of Alzheimer's disease (AD) …
The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster
S Pichler, W Gu, D Hartl, G Gasparoni, P Leidinger… - Neurobiology of …, 2017 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNA molecules, with essential functions in RNA
silencing and post-transcriptional regulation of gene expression. miRNAs appear to regulate …
silencing and post-transcriptional regulation of gene expression. miRNAs appear to regulate …
miR-34a, a microRNA up-regulated in a double transgenic mouse model of Alzheimer's disease, inhibits bcl2 translation
X Wang, P Liu, H Zhu, Y Xu, C Ma, X Dai, L Huang… - Brain research …, 2009 - Elsevier
MicroRNAs (miRNAs) are short noncoding regulatory RNA molecules that modulate protein
expression by inhibiting mRNA translation or promoting mRNA degradation. However, little …
expression by inhibiting mRNA translation or promoting mRNA degradation. However, little …
MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid
M Müller, HB Kuiperij, JA Claassen, B Küsters… - Neurobiology of …, 2014 - Elsevier
MicroRNAs (miRNAs) are small, noncoding RNAs that function in complex networks to
regulate protein expression. In the brain, they are involved in development and synaptic …
regulate protein expression. In the brain, they are involved in development and synaptic …
Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β
MicroRNAs (miRNAs) are small non-coding RNA regulators of protein synthesis that are
essential for normal brain development and function. Their profiles are significantly altered …
essential for normal brain development and function. Their profiles are significantly altered …
Human microRNA (miR-20b-5p) modulates Alzheimer's disease pathways and neuronal function, and a specific polymorphism close to the MIR20B gene influences …
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with loss of cognitive,
executive, and other mental functions, and is the most common form of age-related …
executive, and other mental functions, and is the most common form of age-related …
Differential microRNA expression analyses across two brain regions in Alzheimer's disease
V Dobricic, M Schilling, J Schulz, LS Zhu… - Translational …, 2022 - nature.com
Dysregulation of microRNAs (miRNAs) is involved in the pathogenesis of
neurodegenerative diseases, including Alzheimer's disease (AD). Hitherto, sample sizes …
neurodegenerative diseases, including Alzheimer's disease (AD). Hitherto, sample sizes …
microRNA‐132: A key noncoding RNA operating in the cellular phase of Alzheimer's disease
E Salta, B De Strooper - The FASEB Journal, 2017 - Wiley Online Library
With the consideration of the broad involvement of microRNAs (miRNAs) in the regulation of
molecular networks in the brain, it is not surprising that miRNA dysregulation causes …
molecular networks in the brain, it is not surprising that miRNA dysregulation causes …
The role of microRNAs in Alzheimer's disease and their therapeutic potentials
MicroRNAs (miRNAs) are short, endogenous, non-coding RNAs that post-transcriptionally
regulate gene expression by base pairing with mRNA targets. Altered miRNA expression …
regulate gene expression by base pairing with mRNA targets. Altered miRNA expression …