Chemical and ecotoxicological assessment of poly (amidoamine) dendrimers in the aquatic environment

IJ Suarez, R Rosal, A Rodriguez, A Ucles… - TrAC Trends in …, 2011 - Elsevier
Poly (amidoamine)(PAMAM) dendrimers are attracting great interest as a consequence of
their unique properties as carriers of active molecules in aqueous media, as we expect their …

An Ecotoxicological Study of Poly(amidoamine) Dendrimers-Toward Quantitative Structure Activity Relationships

PC Naha, M Davoren, A Casey… - Environmental science & …, 2009 - ACS Publications
Polyamidoamine (PAMAM) dendrimers of generation G-4, G-5 and G-6 were evaluated for
their aquatic toxicity using the test models Vibrio fischeri, Daphnia magna, Thamnocephalus …

First evidences of PAMAM dendrimer internalization in microorganisms of environmental relevance: A linkage with toxicity and oxidative stress

S Gonzalo, I Rodea-Palomares, F Leganés… - …, 2015 - Taylor & Francis
This article reports novel results on the toxic mechanisms of action of amine-and hydroxyl-
terminated poly (amidoamine)(PAMAM) dendrimers toward microorganisms of …

Qualitative and quantitative analysis of poly (amidoamine) dendrimers in an aqueous matrix by liquid chromatography–electrospray ionization-hybrid quadrupole/time …

A Uclés, MM Ulaszewska, MD Hernando… - Analytical and …, 2013 - Springer
This work introduces a liquid chromatography–electrospray ionization-hybrid
quadrupole/time-of-flight mass spectrometry (LC-ESI-QTOF-MS)-based method for …

Toxicity of PAMAM dendrimers to Chlamydomonas reinhardtii

AN Petit, P Eullaffroy, T Debenest, F Gagné - Aquatic Toxicology, 2010 - Elsevier
In recent decades, a new class of polymeric materials, PAMAM dendrimers, has attracted
marked interest owing to their unique nanoscopic architecture and their hopeful …

Chemical and ecotoxicological assessment of dendrimers in the aquatic environment

MM Ulaszewska, MD Hernando, A Ucles… - Comprehensive …, 2012 - Elsevier
Dendrimers represent a class of polymers with promising applications as nanodevices in
biomedicine and industry. This review provides a comprehensive summary of recent …

Partitioning of Poly(amidoamine) Dendrimers between n-Octanol and Water

J Giri, MS Diallo, WAG III, NF Dalleska… - … science & technology, 2009 - ACS Publications
Dendritic nanomaterials are emerging as key building blocks for a variety of nanoscale
materials and technologies. Poly (amidoamine)(PAMAM) dendrimers were the first class of …

In vitro dose–response effects of poly(amidoamine) dendrimers [amino-terminated and surface-modified with N-(2-hydroxydodecyl) groups] and quantitative …

MD Hernando, P Rosenkranz, MM Ulaszewska… - Analytical and …, 2012 - Springer
This article presents a dose–response study of the effects of two types of third-generation
(G3) and fourth-generation poly (amidoamine)(PAMAM) dendrimers on two cell lines (RTG-2 …

Identification and quantification of poly (amidoamine) PAMAM dendrimers of generations 0 to 3 by liquid chromatography/hybrid quadrupole time‐of‐flight mass …

MM Ulaszewska, MD Hernando… - Rapid …, 2013 - Wiley Online Library
RATIONALE Poly (amidoamine) PAMAM dendrimers are highly water soluble and are used
as flexible scaffolding or nanocontainers to conjugate, complex or encapsulate therapeutic …

Toxicity of pamam‐coated gold nanoparticles in different unicellular models

F Perreault, SP Melegari, CF Fuzinatto… - Environmental …, 2014 - Wiley Online Library
Polyamidoamine (PAMAM) dendrimers are used for many pharmaceutical and biomedical
applications. However, the toxicological risks of several PAMAM‐based compounds are still …