MicroRNAs, a class of small noncoding RNAs, are implicated in controlling a variety of
biological processes. We have shown that leucine deprivation suppresses lipogenesis by …

MicroRNAs are potential therapeutic targets for metabolic diseases. Here, miR-1224-5p was
highly expressed in the livers of mice fed a high-fat diet (HFD) and in obese (ob/ob) mice. To …

Nonalcoholic fatty liver disease (NAFLD) is highly correlated with obesity, and lifestyle
changes to reduce weight remain the main therapeutic approach. The noncoding RNA miR …

MicroRNAs, a class of small non-coding RNAs, are believed to regulate several biological
pathways and processes and are implicated in several diseases. They mostly regulate the …

miR-23a-3p and miR-23b-3p are members of the miR-23~ 27~ 24-2 superfamily. The role of
miR-23a/b-3p in regulating hepatic lipid accumulation is still unknown. Here, we found that …

Background Diet-induced obesity can result in the development of a diverse spectrum of
cardiovascular and metabolic diseases, including type 2 diabetes, dyslipidemia, non …

Non-alcoholic fatty liver diseases (NAFLD) is one of the leading cause of chronic liver
diseases in the world. However, the pathogenesis of NAFLD is still unclear. Emerging …

AIM: To assess the regulatory effect of microRNA-185 (miR-185) on lipid metabolism and the
insulin signalling pathway in human HepG2 hepatocytes and a high-fat diet mouse model …

Background & Aims The paradox of hepatic insulin resistance describes the inability for liver
to respond to bioenergetics hormones in suppressing gluconeogenesis whilst maintaining …

MicroRNAs (miRNAs) are endogenous, noncoding, short, single-stranded RNAs that are
evolutionarily conserved and believed to play a role in controlling a variety of biological …