An atlas of plant full-length RNA reveals tissue-specific and monocots–dicots conserved regulation of poly (A) tail length
Poly (A) tail is a hallmark of eukaryotic messenger RNA and its length plays an essential role
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
Dual function of the messenger RNA cap structure in poly (A)-tail-promoted translation in yeast
The messenger RNA 3′ poly (A) tail critically affects the initiation and control of translation
in eukaryotes,,. By analogy to elements involved in transcription initiation, the poly (A) tail …
in eukaryotes,,. By analogy to elements involved in transcription initiation, the poly (A) tail …
[HTML][HTML] Remodeling of maternal mRNA through poly (A) tail orchestrates human oocyte-to-embryo transition
Y Liu, H Zhao, F Shao, Y Zhang, H Nie… - Nature structural & …, 2023 - nature.com
Abstract Poly (A)-tail-mediated post-transcriptional regulation of maternal mRNAs is vital in
the oocyte-to-embryo transition (OET). Nothing is known about poly (A) tail dynamics during …
the oocyte-to-embryo transition (OET). Nothing is known about poly (A) tail dynamics during …
[HTML][HTML] The molecular basis of coupling between poly (A)-tail length and translational efficiency
In animal oocytes and early embryos, mRNA poly (A)-tail length strongly influences
translational efficiency (TE), but later in development this coupling between tail length and …
translational efficiency (TE), but later in development this coupling between tail length and …
Tales of detailed poly (A) tails
AL Nicholson, AE Pasquinelli - Trends in cell biology, 2019 - cell.com
Poly (A) tails are non-templated additions of adenosines at the 3′ ends of most eukaryotic
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …
[HTML][HTML] Poly (A) inclusive RNA isoform sequencing (PAIso− seq) reveals wide-spread non-adenosine residues within RNA poly (A) tails
Y Liu, H Nie, H Liu, F Lu - Nature communications, 2019 - nature.com
Message RNA poly (A) tails are vital for their function and regulation. However, the full-
length sequence of mRNA isoforms with their poly (A) tails remains undetermined. Here, we …
length sequence of mRNA isoforms with their poly (A) tails remains undetermined. Here, we …
N6-methyladenosine in poly(A) tails stabilize VSG transcripts
IJ Viegas, JP de Macedo, L Serra, M De Niz… - Nature, 2022 - nature.com
RNA modifications are important regulators of gene expression. In Trypanosoma brucei,
transcription is polycistronic and thus most regulation happens post-transcriptionally. N 6 …
transcription is polycistronic and thus most regulation happens post-transcriptionally. N 6 …
Measuring the tail: Methods for poly (A) tail profiling
A Brouze, PS Krawczyk… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Abstract The 3′‐end poly (A) tail is an important and potent feature of most mRNA
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …
ePAT: a simple method to tag adenylated RNA to measure poly (A)-tail length and other 3′ RACE applications
The addition of a poly (A)-tail to the 3′ termini of RNA molecules influences stability,
nuclear export, and efficiency of translation. In the cytoplasm, dynamic changes in the length …
nuclear export, and efficiency of translation. In the cytoplasm, dynamic changes in the length …
Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs
Post-transcriptional gene regulation frequently occurs through elements in mRNA 3′
untranslated regions (UTRs),. Although crucial roles for 3′ UTR-mediated gene regulation …
untranslated regions (UTRs),. Although crucial roles for 3′ UTR-mediated gene regulation …