An atlas of plant full-length RNA reveals tissue-specific and monocots–dicots conserved regulation of poly (A) tail length

J Jia, W Lu, B Liu, H Fang, Y Yu, W Mo, H Zhang, X Jin… - Nature Plants, 2022 - nature.com
Poly (A) tail is a hallmark of eukaryotic messenger RNA and its length plays an essential role
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …

Dual function of the messenger RNA cap structure in poly (A)-tail-promoted translation in yeast

T Preiss, MW Hentze - Nature, 1998 - nature.com
The messenger RNA 3′ poly (A) tail critically affects the initiation and control of translation
in eukaryotes,,. By analogy to elements involved in transcription initiation, the poly (A) tail …

[HTML][HTML] Remodeling of maternal mRNA through poly (A) tail orchestrates human oocyte-to-embryo transition

Y Liu, H Zhao, F Shao, Y Zhang, H Nie… - Nature structural & …, 2023 - nature.com
Abstract Poly (A)-tail-mediated post-transcriptional regulation of maternal mRNAs is vital in
the oocyte-to-embryo transition (OET). Nothing is known about poly (A) tail dynamics during …

[HTML][HTML] The molecular basis of coupling between poly (A)-tail length and translational efficiency

K Xiang, DP Bartel - Elife, 2021 - elifesciences.org
In animal oocytes and early embryos, mRNA poly (A)-tail length strongly influences
translational efficiency (TE), but later in development this coupling between tail length and …

Tales of detailed poly (A) tails

AL Nicholson, AE Pasquinelli - Trends in cell biology, 2019 - cell.com
Poly (A) tails are non-templated additions of adenosines at the 3′ ends of most eukaryotic
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …

[HTML][HTML] Poly (A) inclusive RNA isoform sequencing (PAIso− seq) reveals wide-spread non-adenosine residues within RNA poly (A) tails

Y Liu, H Nie, H Liu, F Lu - Nature communications, 2019 - nature.com
Message RNA poly (A) tails are vital for their function and regulation. However, the full-
length sequence of mRNA isoforms with their poly (A) tails remains undetermined. Here, we …

N6-methyladenosine in poly(A) tails stabilize VSG transcripts

IJ Viegas, JP de Macedo, L Serra, M De Niz… - Nature, 2022 - nature.com
RNA modifications are important regulators of gene expression. In Trypanosoma brucei,
transcription is polycistronic and thus most regulation happens post-transcriptionally. N 6 …

Measuring the tail: Methods for poly (A) tail profiling

A Brouze, PS Krawczyk… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Abstract The 3′‐end poly (A) tail is an important and potent feature of most mRNA
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …

ePAT: a simple method to tag adenylated RNA to measure poly (A)-tail length and other 3′ RACE applications

A Jänicke, J Vancuylenberg, PR Boag, A Traven… - Rna, 2012 - rnajournal.cshlp.org
The addition of a poly (A)-tail to the 3′ termini of RNA molecules influences stability,
nuclear export, and efficiency of translation. In the cytoplasm, dynamic changes in the length …

Formation, regulation and evolution of Caenorhabditis elegans 3′UTRs

CH Jan, RC Friedman, JG Ruby, DP Bartel - Nature, 2011 - nature.com
Post-transcriptional gene regulation frequently occurs through elements in mRNA 3′
untranslated regions (UTRs),. Although crucial roles for 3′ UTR-mediated gene regulation …