Glycine plays two roles in neurotransmission. In caudal areas like the spinal cord and the
brainstem, it acts as an inhibitory neurotransmitter, but in all regions of the CNS, it also works …

Dopamine neurons in the ventral tegmental area (VTA) play an important role in the
motivational systems underlying drug addiction, and recent work has suggested that they …

GLT-1 (EAAT2; slc1a2) is the major glutamate transporter in the brain, and is predominantly
expressed in astrocytes, but at lower levels also in excitatory terminals. We generated a …

To identify glutamate transporters expressed in forebrain neurons, we prepared a cDNA
library from rat forebrain neuronal cultures, previously shown to transport glutamate with …

An emerging preclinical literature suggests that targeting central glucagon-like peptide-1
receptors (GLP-1Rs) may represent a novel approach to treating cocaine use disorder …

Neurons responsible for sensing noxious stimuli and conducting pain signals from periphery
to the spinal cord are predominantly glutamatergic. Members of the SLC1A family of high …

Glutamate plays a pivotal role in regulating drug self-administration and drug-seeking
behavior, and the past decade has witnessed a substantial surge of interest in the role of …

The “One neuron-one neurotransmitter” concept has been challenged frequently during the
last three decades, and the coexistence of neurotransmitters in individual neurons is now …

Glycine transporters are endogenous regulators of the dual functions of glycine, which acts
as a classical inhibitory neurotransmitter at glycinergic synapses and as a modulator of …

Glutamatergic system has an important role in cocaine-seeking behavior. Studies have
reported that chronic exposure to cocaine induces downregulation of glutamate transporter …