[HTML][HTML] Role of autophagy in breast cancer and breast cancer stem cells

Y Han, S Fan, T Qin, J Yang… - International …, 2018 - spandidos-publications.com
Autophagy is a key catabolic process, in which cytosolic cargo is engulfed by the formation
of a double membrane and then degraded through the fusing of autophagosomes with …

[HTML][HTML] Autophagy in breast cancer and its implications for therapy

K Jain, KS Paranandi, S Sridharan… - American journal of …, 2013 - ncbi.nlm.nih.gov
Autophagy is an evolutionarily conserved process of cellular self-digestion that serves as a
mechanism to clear damaged organelles and recycle nutrients. Since autophagy can …

The multifaceted functions of autophagy in breast cancer development and treatment

NJ Niklaus, I Tokarchuk, M Zbinden, AM Schläfli… - Cells, 2021 - mdpi.com
Macroautophagy (herein referred to as autophagy) is a complex catabolic process
characterized by the formation of double-membrane vesicles called autophagosomes …

[HTML][HTML] Towards dual function of autophagy in breast cancer: A potent regulator of tumor progression and therapy response

M Hashemi, MDA Paskeh, S Orouei, P Abbasi… - Biomedicine & …, 2023 - Elsevier
As a devastating disease, breast cancer has been responsible for decrease in life
expectancy of females and its morbidity and mortality are high. Breast cancer is the most …

Autophagy: friend or foe in breast cancer development, progression, and treatment

DE Berardi, PB Campodonico… - … journal of breast …, 2011 - Wiley Online Library
Autophagy is a catabolic process responsible for the degradation and recycling of long‐lived
proteins and organelles by lysosomes. This degradative pathway sustains cell survival …

The importance of autophagy regulation in breast cancer development and treatment

JM Zarzynska - BioMed research international, 2014 - Wiley Online Library
Breast cancer (BC) is a potentially life‐threatening malignant tumor that still causes high
mortality among women. One of the mechanisms through which cancer development could …

Role of autophagy in breast cancer development and progression: opposite sides of the same coin

MA Romero, O Bayraktar Ekmekcigil, BG Bagca… - … Cancer Metastasis and …, 2019 - Springer
The term “autophagy”, which means “self (auto)-eating (phagy)”, describes a catabolic
process that is evolutionarially conserved among all eukaryotes. Although autophagy is …

Autophagy and breast cancer: connected in growth, progression, and therapy

Q Wu, D Sharma - Cells, 2023 - mdpi.com
Despite an increase in the incidence of breast cancer worldwide, overall prognosis has
been consistently improving owing to the development of multiple targeted therapies and …

Roles of autophagy in breast cancer treatment: Target, bystander or benefactor

L Tyutyunyk-Massey, DA Gewirtz - Seminars in cancer biology, 2020 - Elsevier
Despite the availability of largely effective treatments for breast cancer, such as the
combination of aromatase inhibitors or anti-estrogens with cdk4/6 inhibitors for estrogen …

The multifaceted roles of autophagy in tumors—implications for breast cancer

J Debnath - Journal of mammary gland biology and neoplasia, 2011 - Springer
Autophagy is an evolutionarily conserved lysosomal degradation process that is crucial for
adaptation to stress as well as in cellular homeostasis. In cancer, our current understanding …