The pharmacogenomic network responsible for the rapid antidepressant action of ketamine
and concomitant adverse events in patients has been poorly defined. Integrative, multi-scale …

Major depressive disorder is a highly prevalent psychiatric disorder. Despite an extensive
range of treatment options, about a third of patients still struggle to respond to available …

Background: Ketamine has emerged as one of the most promising therapies for treatment-
resistant depression. However, inter-individual variability in response to ketamine is still not …

Ketamine is a multifunctional drug with clinical applications as an anesthetic, pain
management medication, and a fast-acting antidepressant. However, it is also recreationally …

Depression is one of the most common disabling mental disorders. However, first-line
treatments for depression are typically slow-acting. Ketamine, a glutamatergic modulator …

Ketamine is a NMDA receptor antagonist that has a rapid acting antidepressant effect with
high efficacy in treatment-resistant patients. Ketamine is a beneficial antidepressant for …

Background The NMDA receptor antagonist ketamine was found to act as a fast-acting
antidepressant. The effects of single treatment were reported to persist for days to weeks …

Ketamine is a dissociative anesthetic used worldwide for anesthesia, pain management,
treatment resistant depression (TRD) and suicidality. Predictors of antidepressant response …

Low-dose ketamine is an efficacious antidepressant for treatment-resistant unipolar and
bipolar depressed patients. Major Depression Disorder patients receiving a single infusion …

Ketamine is a widely used clinical drug that has several functional and clinical applications,
including its use as an anaesthetic, analgesic, anti-depressive, anti-suicidal agent, among …