We have demonstrated previously the regulation of Cl−/HCO 3− exchange activity by the
cystic fibrosis transmembrane conductance regulator (CFTR) in model systems of cells …

A central function of cystic fibrosis transmembrane conductance regulator (CFTR)-
expressing tissues is the secretion of fluid containing 100–140 mmHCO 3−. High levels of …

The cystic fibrosis transmembrane conductance regulator (CFTR) is vital for Cl–and HCO 3−
transport in many epithelia. As the HCO 3− concentration in epithelial secretions varies and …

Cystic fibrosis results from defective Cl-channel activity mediated by the cystic fibrosis
transmembrane conductance regulator (CFTR) gene product. In the gastrointestinal tract this …

Plasma membrane chloride transport by the cystic fibrosis transmembrane conductance
regulator (CFTR) may be regulated by cellular processes that affect the cycling of CFTR with …

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP and cGMP-
regulated chloride channel critical to the regulation of intestinal fluid, chloride, and …

Although loss of cystic fibrosis transmembrane conductance regulator (CFTR)-mediated Cl-
channel function is common to all epithelia in cystic fibrosis (CF) patients, the severity of …

Cystic fibrosis is a fatal inherited disease that is caused by mutations in the gene encoding a
cAMP-activated chloride channel, the cystic fibrosis transmembrane conductance regulator …

The cystic fibrosis transmembrane conductance regulator (CFTR) 1 forms a Cl channel that
is an essential component of epithelial Cl transport systems in many organs, including the …

Pancreatic duct cells secrete bicarbonate-rich fluids, which are important for maintaining the
patency of pancreatic ductal trees as well as intestinal digestive function. The bulk of …