Ex vivo evaluation of N-(3-[18F] fluoropropyl)-2β-carbomethoxy-3β-(4-fluorophenyl) nortropane in rats
T Koivula, P Marjamäki, M Haaparanta… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION: The dopamine transporter (DAT) ligand N-(3-fluoropropyl)-2β-
carbomethoxy-3β-(4-fluorophenyl) nortropane (β-CFT-FP) was labeled with fluorine-18, and …
carbomethoxy-3β-(4-fluorophenyl) nortropane (β-CFT-FP) was labeled with fluorine-18, and …
Comparison of 2β-Carbomethoxy-3β-(4-[18F]Fluorophenyl)Tropane and N-(3-[18F]Fluoropropyl)-2β-Carbomethoxy-3β-(4-Fluorophenyl)Nortropane, Tracers for …
P Marjamäki, M Haaparanta, S Forsback… - Molecular imaging and …, 2010 - Springer
Purpose This study compares 2β-carbomethoxy-3β-(4-[18 F] fluorophenyl) tropane ([18 F] β-
CFT) and N-(3-[18 F] fluoropropyl)-2β-carbomethoxy-3β-(4-fluorophenyl) nortropane ([18 F] …
CFT) and N-(3-[18 F] fluoropropyl)-2β-carbomethoxy-3β-(4-fluorophenyl) nortropane ([18 F] …
Radiosynthesis of [18F] N-(3-Fluoropropyl)-2-β-Carbomethoxy-3-β-(4-Bromophenyl) Nortropane and the regional brain uptake in non human primate using PET
T Chaly, RM Baldwin, JL Neumeyer, MJ Hellman… - Nuclear medicine and …, 2004 - Elsevier
A synthetic procedure for the preparation of [18F] FPCBT, an imaging agent for the
dopamine transporter (DAT), has been developed. The radiosynthesis was carried out in a …
dopamine transporter (DAT), has been developed. The radiosynthesis was carried out in a …
Potential of [18F]β‐CFT‐FE (2β‐carbomethoxy‐3β‐(4‐fluorophenyl)‐8‐(2‐[18F]fluoroethyl)nortropane) as a dopamine transporter ligand: A PET study in the …
N Harada, H Ohba, D Fukumoto, T Kakiuchi… - Synapse, 2004 - Wiley Online Library
A dopamine transporter (DAT) ligand 2β‐carbomethoxy‐3β‐(4‐fluoro‐phenyl)‐8‐(2‐[18F]
fluoroethyl) nortropane ([18F] β‐CFT‐FE) was synthesized and evaluated in comparison …
fluoroethyl) nortropane ([18F] β‐CFT‐FE) was synthesized and evaluated in comparison …
PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements
18F-2β-Carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl) nortropane (18F-FECNT), a
PET radioligand for the dopamine transporter (DAT), generates a radiometabolite that enters …
PET radioligand for the dopamine transporter (DAT), generates a radiometabolite that enters …
Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2β-carbomethoxy-3β-(4′-tolyl) nortropane (LBT-999) as a highly promising fluorinated ligand for the …
S Chalon, H Hall, W Saba, L Garreau, F Dollé… - … of Pharmacology and …, 2006 - ASPET
In the aim to develop an efficient fluorinated probe for positron emission tomography (PET)
exploration of the dopamine transporter (DAT), we studied several in vitro and in vivo …
exploration of the dopamine transporter (DAT), we studied several in vitro and in vivo …
Deuterated [18F] fluoroethyl tropane analogs as dopamine transporter probes: Synthesis and biological evaluation
Q Li, Q Hu, J Tang, Y Fang, C Liu, J Liu, M Qi… - Nuclear Medicine and …, 2023 - Elsevier
Introduction The dopamine transporter (DAT) is vitally correlated with Parkinson's disease
(PD) and other neurodegenerative diseases. Non-invasive imaging of DAT contributes to …
(PD) and other neurodegenerative diseases. Non-invasive imaging of DAT contributes to …
Synthesis, Fluorine-18 Radiolabeling, and Biological Evaluation of N-((E)-4-Fluorobut-2-en-1-yl)-2β-carbomethoxy-3β-(4′-halophenyl)nortropanes: Candidate …
JS Stehouwer, LM Daniel, P Chen, RJ Voll… - Journal of medicinal …, 2010 - ACS Publications
The N-(E)-fluorobutenyl-3β-(para-halo-phenyl) nortropanes 9− 12 were synthesized as
ligands of the dopamine transporter (DAT) for use as 18F-labeled positron emission …
ligands of the dopamine transporter (DAT) for use as 18F-labeled positron emission …
18F-labeled FECNT: a selective radioligand for PET imaging of brain dopamine transporters
MM Goodman, CD Kilts, R Keil, B Shi… - Nuclear medicine and …, 2000 - Elsevier
Fluorine-18 labeled 2β-carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl) nortropane
(FECNT) was synthesized in the development of a dopamine transporter (DAT) imaging …
(FECNT) was synthesized in the development of a dopamine transporter (DAT) imaging …
Biodistribution and radiation dosimetry of the dopamine transporter ligand [18F] FECNT
TA Deterding, JR Votaw, CK Wang… - Journal of Nuclear …, 2001 - Soc Nuclear Med
18F-labeled 2 β-carbomethoxy-3β-(4-chlorophenyl)-8-(− 2-fluoroethyl) nortropane ([18F]
FECNT) is a recently developed dopamine transporter ligand with potential applications in …
FECNT) is a recently developed dopamine transporter ligand with potential applications in …