Study design and outcome measures in studies on aneurysmal subarachnoid hemorrhage

IC van der Schaaf, YM Ruigrok, GJE Rinkel, A Algra… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—Methods of performing and reporting randomized clinical trials
(RCTs) are available, but weaknesses still occur. For observational studies, methodology is …

Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for healthcare professionals from a special writing group of the Stroke Council …

JB Bederson, ES Connolly Jr, HH Batjer, RG Dacey… - Stroke, 2009 - Am Heart Assoc
Subarachnoid hemorrhage (SAH) is a common and fre-quently devastating condition,
accounting for 5% of all strokes and affecting as many as 30 000 Americans each year. 1, 2 …

Guidelines for the management of aneurysmal subarachnoid hemorrhage: a guideline for healthcare professionals from the American Heart Association/American …

ES Connolly Jr, AA Rabinstein, JR Carhuapoma… - Stroke, 2012 - Am Heart Assoc
Purpose—The aim of this guideline is to present current and comprehensive
recommendations for the diagnosis and treatment of aneurysmal subarachnoid hemorrhage …

SAHIT investigators—on the outcome of some subarachnoid hemorrhage clinical trials

RL Macdonald, B Jaja, MD Cusimano… - Translational stroke …, 2013 - Springer
Outcome of patients with aneurysmal subarachnoid hemorrhage (SAH) has improved over
the last decades. Yet, case fatality remains nearly 40% and survivors often have permanent …

The Subarachnoid Hemorrhage International Trialists (SAHIT) Repository: advancing clinical research in subarachnoid hemorrhage

BNR Jaja, D Attalla, RL Macdonald, TA Schweizer… - Neurocritical care, 2014 - Springer
Researchers and other stakeholders continue to express concern about the failure of
randomized clinical trials (RCT) in subarachnoid hemorrhage (SAH) to show efficacy of new …

Impact of medical treatment on the outcome of patients after aneurysmal subarachnoid hemorrhage

FH Vermeij, D Hasan, HWC Bijvoet, CJJ Avezaat - Stroke, 1998 - Am Heart Assoc
Background and Purpose—The rationale behind early aneurysm surgery in patients with
subarachnoid hemorrhage (SAH) is the prevention of rebleeding as early as possible after …

Subarachnoid hemorrhage international trialists data repository (SAHIT)

RL Macdonald, MD Cusimano, N Etminan, D Hanggi… - World neurosurgery, 2013 - Elsevier
The outcome of patients with aneurysmal subarachnoid hemorrhage (SAH) has improved
slowly over the past 25 years. This improvement may be due to early aneurysm repair by …

Improved survival after aneurysmal subarachnoid hemorrhage: review of management during a 12-year period

KG Cesarini, HG Hårdemark, L Persson - Journal of neurosurgery, 1999 - thejns.org
Object. Based on the concept that unfavorable clinical outcome after aneurysmal
subarachnoid hemorrhage (SAH), to a large extent, is a consequence of all ischemic insults …

Guidelines for the neurocritical care management of aneurysmal subarachnoid hemorrhage

MM Treggiari, AA Rabinstein, KM Busl, MM Caylor… - Neurocritical care, 2023 - Springer
Background The neurointensive care management of patients with aneurysmal
subarachnoid hemorrhage (aSAH) is one of the most critical components contributing to …

Prioritization and timing of outcomes and endpoints after aneurysmal subarachnoid hemorrhage in clinical trials and observational studies: proposal of a …

MN Stienen, JM Visser-Meily, TA Schweizer, D Hänggi… - Neurocritical care, 2019 - Springer
Introduction In studies on aneurysmal subarachnoid hemorrhage (SAH), substantial
variability exists in the use and timing of outcomes and endpoints, which complicates …