Abstract PR05: Single-cell transcriptomics reveals shared and subtype-specific vulnerabilities of the tumor-microenvironment ecosystems in peripheral T-cell …
WH Wendy Lin, AW Wang, BB Shih, JBF Reynier… - Blood Cancer …, 2024 - AACR
Peripheral T-cell lymphomas (PTCL) are heterogeneous and highly aggressive hematologic
malignancies with dismal outcomes, highlighting the need for novel targeted therapies …
malignancies with dismal outcomes, highlighting the need for novel targeted therapies …
[HTML][HTML] Genomic and transcriptomic profiling of peripheral T cell lymphoma reveals distinct molecular and microenvironment subtypes
YH Huang, YR Qiu, QL Zhang, MC Cai, H Yu… - Cell Reports …, 2024 - cell.com
Peripheral T cell lymphoma (PTCL) is a heterogeneous group of non-Hodgkin's lymphomas
varying in clinical, phenotypic, and genetic features. The molecular pathogenesis and the …
varying in clinical, phenotypic, and genetic features. The molecular pathogenesis and the …
[HTML][HTML] S237: THE GENETIC SUBTYPES AND THE TUMOR MICROENVIRONMENT SIGNATURES ARE ASSOCIATED WITH DISTINCT OUTCOMES IN …
Y Suehara, K Sakamoto, M Fujisawa, K Fukumoto… - …, 2023 - journals.lww.com
Background: Emerging evidence suggests the prognostic impact of the tumor
microenvironment (TME) in peripheral T-cell lymphomas (PTCLs). Aims: To better …
microenvironment (TME) in peripheral T-cell lymphomas (PTCLs). Aims: To better …
[HTML][HTML] P1205: A LIVING PATIENT-DERIVED BIOREPOSITORY FOSTERING MICROENVIRONMENT DISSECTION IN T-CELL LYMPHOMA
Background: The contribution of the tumor microenvironment (TME) to Peripheral T-Cell
Lymphomas (PTCL) pathogenesis has been increasingly recognized. Despite recent …
Lymphomas (PTCL) pathogenesis has been increasingly recognized. Despite recent …
[HTML][HTML] Precise diagnosis and treatment for peripheral T-cell lymphomas: From pathogenic mechanisms to innovative approaches
Peripheral T-cell lymphomas (PTCLs) encompass a diverse group of aggressive non-
Hodgkin's lymphomas originating from mature T lymphocytes. Despite their relatively low …
Hodgkin's lymphomas originating from mature T lymphocytes. Despite their relatively low …
Molecular Investigation into the Biologic and Prognostic Elements of Peripheral T-cell Lymphoma with Regulators of Tumor Microenvironment Signaling Explored in …
T Herek - 2021 - digitalcommons.unmc.edu
Peripheral T-cell lymphoma (PTCL) is heterogenous group of mature T-cell neoplasms
characterized by distinctive transcriptional and genetic lesions. Herein, we investigated …
characterized by distinctive transcriptional and genetic lesions. Herein, we investigated …
A Patient-Derived T-Cell Lymphoma Biorepository Uncovers New Pathogenetic Mechanisms and Host-Related Therapeutic Vulnerabilities
T-cell lymphomas (TCLs) comprise a heterogeneous group of malignancies. Current
therapeutic options remain limited, partly given the scarcity of representative preclinical …
therapeutic options remain limited, partly given the scarcity of representative preclinical …
[HTML][HTML] Molecular heterogeneity in peripheral T-cell lymphoma, not otherwise specified revealed by comprehensive genetic profiling
Y Watatani, Y Sato, H Miyoshi, K Sakamoto, K Nishida… - Leukemia, 2019 - nature.com
Peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) is a diagnosis of
exclusion, being the most common entity in mature T-cell neoplasms, and its molecular …
exclusion, being the most common entity in mature T-cell neoplasms, and its molecular …
[HTML][HTML] A survey of the therapeutic landscape in peripheral T-cell lymphomas: the importance of expert hematopathology review in the era of targeted therapies and …
AJ Scott, CW Ross, AM Gabali… - Annals of Lymphoma, 2019 - aol.amegroups.org
Peripheral T-cell lymphomas (PTCL) remain a diagnostic challenge, and the most common
subtype remains “unspecified”. However, improved understanding of the transcriptional and …
subtype remains “unspecified”. However, improved understanding of the transcriptional and …
[HTML][HTML] High-Dimensional and Single-Cell Transcriptome Analysis of AITL Tumor Microenvironment Reveals Gross Expansion of Novel Dysfunctional CD8+ T Cell …
JC Pritchett, ZZ Yang, H Kim, JC Villasboas… - Blood, 2020 - Elsevier
BACKGROUND: Angioimmunoblastic T cell lymphoma (AITL) has a unique histological
profile comprised of a relatively small number of malignant CD4+ T-cells of TFH phenotype …
profile comprised of a relatively small number of malignant CD4+ T-cells of TFH phenotype …
相关搜索
- peripheral t cell lymphoma
- tumor microenvironment cell phenotypes
- tumor microenvironment cell populations
- tumor microenvironment transcriptome analysis
- regulators of tumor microenvironment
- tumor microenvironment signatures
- tumor microenvironment global shift
- precision medicine targeted therapies
- therapeutic landscape targeted therapies
- transcriptome analysis cell phenotypes
- transcriptome analysis cell populations
- global shift cell phenotypes
- global shift cell populations