It has been speculated that IL‐1 genes play a crucial role in the genetic predisposition to
duodenal ulcer upon H. pylori infection by modulating the host immune response. In the …

Background. The host genetic factors that determine the clinical outcomes for Helicobacter
pylori‐infected individuals remain unclear. Aims. To elucidate the relations among …

Background: Previous studies imply that IL-1 and IL-8 gene variations may play a crucial
role in the genetic predisposition to different gastric disorders upon H. pylori infection …

BACKGROUND AND AIMS:: Chronic H. pylori infection is the main cause of ulcer disease
which depicts a major burden of our healthy care systems. The individual host immune …

Cytokine genes taking part in the immunological response to Helicobacter pylori infection
are good candidates to study for genetic predisposition to duodenal ulcer disease (DU) …

The proinflammatory cytokine interleukin-1 has been implicated in host susceptibility to
Helicobacter pylori-associated disease. Recent studies suggest that this susceptibility may …

Background and aims. Helicobacter pylori infection almost invariably causes chronic
gastritis, but only a proportion of the infected subjects develop peptic ulcers. The local …

BACKGROUND: Many of the pathogenic effects of Helicobacter pylori infection are related to
chronic active inflammation, which is controlled and maintained by the complex interplay of …

Introduction: Helicobacter pylori infection is associated with gastritis, peptic ulcer disease
and gastric carcinoma. The severity of damage is determined by the interplay between …

Recent studies have reported the association of a pro‐inflammatory profile of genetic
polymorphisms in IL‐1B, IL‐1RN, TNF‐A, and IL‐10 genes with an increased risk of non …