T cell responses to myelin basic protein (MBP) may play an important role in the
pathogenesis of multiple sclerosis (MS). If MBP‐reactive T cells are involved in the disease …

Previous findings from our laboratory demonstrated that some clonally expanded
cerebrospinal fluid (CSF) B cells from MS patients exhibit diminished mutation targeting …

Demyelination and axonal loss have been described as the histological hallmarks of
inflammatory lesions of multiple sclerosis (MS) and are the pathological correlates of …

B cells and their secreted products participate in the intricate network of pathogenic and
regulatory immune responses. In human autoimmune diseases like rheumatoid arthritis …

B cells are one of the key players in the pathogenesis of multiple sclerosis (MS). The
peripheral B cell distributions are similar in healthy persons and MS patients. In healthy …

B cells have long played an enigmatic role in the scenario of multiple sclerosis
pathogenesis. This review summarizes recent progress in our understanding of B‐cell …

There is evidence that B cells are involved in the pathophysiology of many neurological
diseases, either in a causative or contributory role, via production of autoantibodies, cytokine …

Clonally expanded populations of B cells carrying somatic mutations of Ig variable (V) region
genes have been detected in the CNS of subjects with multiple sclerosis (MS), suggesting …

The role of B cells in the pathogenesis of Multiple Sclerosis (MS) is incompletely understood.
Here we define a possible role for B cells as myelin-specific antigen presenting cells (B …

Introduction Multiple sclerosis (MS) is a chronic autoimmune disorder that affects the central
nervous system and compromises the health and well-being of millions of people worldwide …