Multi-compartment encapsulation of communicating droplets and droplet networks in hydrogel as a model for artificial cells
Constructing a cell mimic is a major challenge posed by synthetic biologists. Efforts to this
end have been primarily focused on lipid-and polymer-encapsulated containers, liposomes …
end have been primarily focused on lipid-and polymer-encapsulated containers, liposomes …
Vesicle-based artificial cells: materials, construction methods and applications
The construction of artificial cells with specific cell-mimicking functions helps to explore
complex biological processes and cell functions in natural cell systems and provides an …
complex biological processes and cell functions in natural cell systems and provides an …
Facile and programmable capillary-induced assembly of prototissues via hanging drop arrays
C Qi, X Ma, J Zhong, J Fang, Y Huang, X Deng… - ACS …, 2023 - ACS Publications
An important goal for bottom-up synthetic biology is to construct tissue-like structures from
artificial cells. The key is the ability to control the assembly of the individual artificial cells …
artificial cells. The key is the ability to control the assembly of the individual artificial cells …
Bilayer networks within a hydrogel shell: a robust chassis for artificial cells and a platform for membrane studies
DK Baxani, AJL Morgan, WD Jamieson… - Angewandte Chemie …, 2016 - Wiley Online Library
The ability to make artificial lipid bilayers compatible with a wide range of environments, and
with sufficient structural rigidity for manual handling, would open up a wealth of opportunities …
with sufficient structural rigidity for manual handling, would open up a wealth of opportunities …
Lipid-coated hydrogel shapes as components of electrical circuits and mechanical devices
Recently, two-dimensional networks of aqueous droplets separated by lipid bilayers, with
engineered protein pores as functional elements, were used to construct millimeter-sized …
engineered protein pores as functional elements, were used to construct millimeter-sized …
Constructing vesicle-based artificial cells with embedded living cells as organelle-like modules
There is increasing interest in constructing artificial cells by functionalising lipid vesicles with
biological and synthetic machinery. Due to their reduced complexity and lack of evolved …
biological and synthetic machinery. Due to their reduced complexity and lack of evolved …
Engineering multi-compartment vesicle networks
Vesicles serve important functions in the construction of artificial cells. They facilitate
biochemical reactions by confining reactants and products in space, and delineate the …
biochemical reactions by confining reactants and products in space, and delineate the …
Interface engineering in multiphase systems toward synthetic cells and organelles: From soft matter fundamentals to biomedical applications
Synthetic cells have a major role in gaining insight into the complex biological processes of
living cells; they also give rise to a range of emerging applications from gene delivery to …
living cells; they also give rise to a range of emerging applications from gene delivery to …
A new design for an artificial cell: polymer microcapsules with addressable inner compartments that can harbor biomolecules, colloids or microbial species
AX Lu, H Oh, JL Terrell, WE Bentley… - Chemical science, 2017 - pubs.rsc.org
Eukaryotic cells have an architecture consisting of multiple inner compartments (organelles)
such as the nucleus, mitochondria, and lysosomes. Each organelle is surrounded by a …
such as the nucleus, mitochondria, and lysosomes. Each organelle is surrounded by a …
Giant polymersome protocells dock with virus particle mimics via multivalent glycan-lectin interactions
A Kubilis, A Abdulkarim, AM Eissa, NR Cameron - Scientific reports, 2016 - nature.com
Despite the low complexity of their components, several simple physical systems, including
microspheres, coacervate droplets and phospholipid membrane structures (liposomes) …
microspheres, coacervate droplets and phospholipid membrane structures (liposomes) …
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