Nocardia rubra cell wall skeleton (N-CWS) was found to synergistically augment lymphokine-
activated killer (LAK) cell generation from human peripheral blood mononuclear cells …

C57BL/6 mice inoculated ip with 3LL tumor cells were treated by local combination therapy
with Nocardia rubra cell wall skeleton (N-CWS) and recombinant interleukin 2 (rIL-2). The …

The present study elucidated that N-CWS augments the cytolytic activity against 3LL tumor
cells of LAK cells from N-CWS-immunized mice administered ip with rIL-2. This …

Four‐hour exposure of C3H/HeN mouse spleen cells to Nocardia rubra cell wall skeleton (N‐
CWS) before 4‐day culture with a suboptimal dose of human recombinant interleukin 2 (rIL …

Combination of an ip injection of Nocardia rubra cell wall skeleton (N‐CWS) and 3 daily sc
injections of human recombinant interleukin 2 (rIL 2) into C3H/HeN mice resulted not only in …

Lymphokine-activated killer activity in vivo (endogenous LAK activity) was found to be
augmented by combined administration of lentinan, a β (1–3) glucan with β-1, 6 branches …

Background: A variety of molecules produced by both tumor cells and normal cells reduce
the activity of lymphokine-activated killer (LAK) cells. We tested the possible cross-regulation …

The progenitor and effector cell phenotype of lymphokine-activated killer (LAK) cells
generated in F344 rats by recombinant human interleukin 2 (IL-2)(rIL-2) were analyzed …

The role of recombinant granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) in
monocyte‐mediated up‐regulation of lymphokine‐activated killer (LAK) ell induction by IL‐2 …

Roles of monocytes and cytokines were investigated on LAK induction from T and NK cells.
Monocytes augmented more T-LAK induction than did NK-LAK. Expression of IL-β, TNF-α …