Novel behavioral and pharmacological characterization of spontaneous stereotypy in the deer mouse

PW Wolmarans - 2015 - repository.nwu.ac.za
Obsessive-compulsive disorder (OCD) is a psychiatric condition that is characterized by two
main symptom cohorts, namely recurrent inappropriate thoughts (obsessions) and …

Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder

S Korff, DJ Stein, BH Harvey - Progress in Neuro-Psychopharmacology and …, 2008 - Elsevier
Stereotypy is an important manifestation of obsessive compulsive disorder (OCD). OCD
involves disturbed serotonin and dopamine pathways, and demonstrates a selective …

Reappraisal of spontaneous stereotypy in the deer mouse as an animal model of obsessive-compulsive disorder (OCD): response to escitalopram treatment and …

DW Wolmarans, L Brand, DJ Stein… - Behavioural brain research, 2013 - Elsevier
Obsessive-compulsive disorder (OCD) is characterized by recurrent thoughts and repetitive
motor actions. Hyposerotonergic signalling in the cortico-striatal circuitry is believed to be …

Stereotypical behaviour in the deer mouse (Peromyscus Maniculatus bairdii): a pharmacological investigation of the frontal–cortico–striatal serotonergic system

PDW Wolmarans - 2011 - repository.nwu.ac.za
Obsessive–compulsive disorder (OCD) is a psychiatric condition that is characterized by two
main symptom cohorts, namely recurrent inappropriate thoughts (obsessions) and …

Molecular and pharmacological studies into a mouse model (Peromyscus maniculatus bairdii) of obsessive compulsive disorder

S Korff - 2007 - repository.nwu.ac.za
There have been various attempts to develop animal models of obsessive compulsive
disorder (OCD) in the hope that they may provide a means to better understand and treat …

Spontaneous alternation and stereotypical behaviour in deer mice: response to escitalopram and levetiracetam

M de Ridder, D Mograbi… - Behavioural …, 2022 - journals.lww.com
Obsessive-compulsive disorder is varyingly associated with cognitive impairment, that is,
deficits in spatial working memory, although it seems unlikely that this is generalised across …

Anxiety-like behaviour and adenosinergic processes in compulsive-like deer mice (Peromyscus maniculatus bairdii)

D Saaiman - 2023 - repository.nwu.ac.za
Obsessive-compulsive disorder (OCD) 1 is characterized by recurring thoughts (obsessions)
and rigid repetition of certain mental or behavioral actions (compulsions) that are often …

A pharmacological and behavioural investigation of anxiety in the deer mouse model of obsessive-compulsive disorder

M Prinsloo - 2021 - repository.nwu.ac.za
Obsessive-compulsive disorder (OCD) 1 is a chronic, debilitating psychiatric disorder with a
global lifetime prevalence rate of 2.0%-2.9% and which generally manifests in early …

Excessive nest building is a unique behavioural phenotype in the deer mouse model of obsessive–compulsive disorder

DW Wolmarans, DJ Stein… - Journal of …, 2016 - journals.sagepub.com
Obsessive–compulsive disorder (OCD) is a phenotypically heterogeneous condition
characterised by time-consuming intrusive thoughts and/or compulsions. Irrespective of the …

Cognitive flexibility in the deer mouse model of obsessive-compulsive disorder and its response to serotonin and adenosine modulation

JP Engelbrecht - 2021 - repository.nwu.ac.za
Obsessive-compulsive disorder (OCD) 1 is a phenotypically heterogeneous psychiatric
disorder characterised by repetitive and ritualised behaviours (compulsions), that are …