Leptin in osteoarthritis and rheumatoid arthritis: player or bystander?
D Ait Eldjoudi, A Cordero Barreal… - International Journal of …, 2022 - mdpi.com
White adipose tissue (WAT) is a specialized tissue whose main function is lipid synthesis
and triglyceride storage. It is now considered as an active organ secreting a plethora of …
and triglyceride storage. It is now considered as an active organ secreting a plethora of …
Adipokines in psoriatic arthritis patients: the correlations with osteoclast precursors and bone erosions
Y Xue, L Jiang, Q Cheng, H Chen, Y Yu, Y Lin… - PLoS …, 2012 - journals.plos.org
Significant bone remodeling with disordered osteoclastogenesis has been implicated in the
pathogenesis of psoriatic arthritis (PsA). And there is a high prevalence of the metabolic …
pathogenesis of psoriatic arthritis (PsA). And there is a high prevalence of the metabolic …
Serum adipokine levels in rheumatoid arthritis patients and their contributions to the resistance to treatment
KS Kim, HM Choi, HI Ji, R Song… - Molecular …, 2014 - spandidos-publications.com
The aim of this study was to determine whether disease activity and the type of therapy
differentially modulate serum adipokine levels in patients with rheumatoid arthritis (RA), and …
differentially modulate serum adipokine levels in patients with rheumatoid arthritis (RA), and …
Visfatin promotes IL-6 and TNF-α production in human synovial fibroblasts by repressing miR-199a-5p through ERK, p38 and JNK signaling pathways
Osteoarthritis (OA), an inflammatory form of arthritis, is characterized by synovial
inflammation and cartilage destruction largely influenced by two key proinflammatory …
inflammation and cartilage destruction largely influenced by two key proinflammatory …
Biomechanics, obesity, and osteoarthritis. The role of adipokines: When the levee breaks
Osteoarthritis is a high‐incidence painful and debilitating disease characterized by
progressive degeneration of articular joints, which indicates a breakdown in joint …
progressive degeneration of articular joints, which indicates a breakdown in joint …
Adiponectin‐mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis
KW Frommer, B Zimmermann, FMP Meier… - Arthritis & …, 2010 - Wiley Online Library
Objective Rheumatoid arthritis (RA) is associated with increased production of adipokines,
which are cytokine‐like mediators that are produced mainly in adipose tissue but also in …
which are cytokine‐like mediators that are produced mainly in adipose tissue but also in …
Adipokines as potential biomarkers in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune disease
characterized by severe joint injury. Recently, research has been focusing on the possible …
characterized by severe joint injury. Recently, research has been focusing on the possible …
Adipocytokines are associated with radiographic joint damage in rheumatoid arthritis
YH Rho, J Solus, T Sokka, A Oeser… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Obesity protects against radiographic joint damage in rheumatoid arthritis (RA)
through poorly defined mechanisms. Adipocytokines are produced in adipose tissue and …
through poorly defined mechanisms. Adipocytokines are produced in adipose tissue and …
[PDF][PDF] Response of human rheumatoid arthritis osteoblasts and osteoclasts to adiponectin
G Krumbholz, S Junker, FMP Meier… - Clin. Exp …, 2017 - clinexprheumatol.org
Objective Adiponectin is an effector molecule in the pathophysiology of rheumatoid arthritis,
eg by inducing cytokines and matrix degrading enzymes in synovial fibroblasts. There is …
eg by inducing cytokines and matrix degrading enzymes in synovial fibroblasts. There is …
Adipokines as targets in musculoskeletal immune and inflammatory diseases
M González-Rodríguez, C Ruiz-Fernández… - Drug Discovery …, 2022 - Elsevier
Adipokines are the principal mediators in adipose signaling. Nevertheless, besides their role
in energy storage, these molecules can be produced by other cells, such as immune cells or …
in energy storage, these molecules can be produced by other cells, such as immune cells or …