Multifaceted roles of adiponectin in rheumatoid arthritis

D Liu, S Luo, Z Li - International Immunopharmacology, 2015 - Elsevier
Adiponectin is a circulating hormone with pleiotropic functions in lipid and glucose
metabolism secreted by adipocytes. It plays a beneficial role in cardiovascular functions and …

Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and …

HM Choi, YA Lee, SH Lee, SJ Hong, DH Hahm… - Arthritis research & …, 2009 - Springer
Introduction The role of adiponectin in the pathogenesis of arthritis is still controversial. This
study was performed to examine whether adiponectin is involved in joint inflammation and …

Role of adiponectin in the pathogenesis of rheumatoid arthritis

K Szumilas, P Szumilas… - International journal of …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a systemic chronic inflammatory autoimmune joint disease,
characterized by progressive articular damage and joint dysfunction. One of the symptoms of …

Visfatin connection: present and future in osteoarthritis and osteoporosis

E Franco-Trepat, M Guillán-Fresco… - Journal of clinical …, 2019 - mdpi.com
Musculoskeletal pathologies (MSPs) such as osteoarthritis (OA) and osteoporosis (OP), are
a set of disorders that cause severe pain, motion difficulties, and even permanent disability …

Changes in plasma levels of fat-derived hormones adiponectin, leptin, resistin and visfatin in patients with rheumatoid arthritis

M Otero, R Lago, R Gomez, F Lago… - Annals of the …, 2006 - ard.bmj.com
Background: Rheumatoid arthritis is a chronic autoimmune inflammatory condition
characterised by polyarthritis and severe change in body mass and neuroendocrine …

Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

S Pallu, PJ Francin, C Guillaume… - Arthritis research & …, 2010 - Springer
Introduction Increasing evidence support the regulatory role of leptin in osteoarthritis (OA).
As high circulating concentrations of leptin disrupt the physiological function of the adipokine …

Role of anti-inflammatory adipokines in obesity-related diseases

K Ohashi, R Shibata, T Murohara, N Ouchi - Trends in endocrinology & …, 2014 - cell.com
Obesity results in many health complications. Accumulating evidence indicates that the
obese state is characterized by chronic low-grade inflammation, thereby leading to the …

A complex relationship between visfatin and resistin and microRNA: an in vitro study on human chondrocyte cultures

S Cheleschi, N Giordano, N Volpi, S Tenti… - International Journal of …, 2018 - mdpi.com
Growing evidence indicates the important role of adipokines and microRNA (miRNA) in
osteoarthritis (OA) pathogenesis. The purpose of the present study was to investigate the …

Serum adipokines and adipose tissue distribution in rheumatoid arthritis and ankylosing spondylitis. A comparative study

É Toussirot, É Grandclément, B Gaugler… - Frontiers in …, 2013 - frontiersin.org
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are inflammatory rheumatic
diseases that may modify body composition. Adipose tissue has the ability to release a wide …

Elevations in adipocytokines and mortality in rheumatoid arthritis

JF Baker, BR England, MD George, K Wysham… - …, 2022 - academic.oup.com
Objectives This study assessed whether circulating levels of adiponectin and leptin are
associated with higher mortality in patients with RA. Methods Participants were adults from …