Evaluation of basophil activation in food allergy: present and future applications

WG Shreffler - Current opinion in allergy and clinical immunology, 2006 - journals.lww.com
Although in their early stages, direct basophil activation tests may prove to be useful in the
clinic. Indirect basophil activation studies are useful when applied to compare functional …

Basophil activation test in food allergy: is it ready for real-time?

T Keswani, SU Patil - Current opinion in allergy and clinical …, 2021 - journals.lww.com
Basophil activation test in food allergy: is it ready for re... : Current Opinion in Allergy and
Clinical Immunology Basophil activation test in food allergy: is it ready for real-time? : Current …

Road map for the clinical application of the basophil activation test in food allergy

AF Santos, WG Shreffler - Clinical & Experimental Allergy, 2017 - Wiley Online Library
The diagnosis of IgE‐mediated food allergy based solely on the clinical history and the
documentation of specific IgE to whole allergen extract or single allergens is often …

Human basophils: a unique biological instrument to detect the allergenicity of food

V Sabato, A Van Hengel… - … : official organ of …, 2011 - repository.uantwerpen.be
Background: Labeling of major food allergens is mandatory for the safety of allergic
consumers. Although enzyme-linked immunosorbent assay, polymerase chain reaction, and …

Basophil activation tests: time for a reconsideration

AP Uyttebroek, V Sabato, MA Faber, N Cop… - Expert review of …, 2014 - Taylor & Francis
Challenges in in vitro allergy diagnostics lie in the development of accessible and reliable
assays allowing identification of all offending allergens and cross-reactive structures. Flow …

Basophil activation test: mechanisms and considerations for use in clinical trials and clinical practice

AF Santos, O Alpan, HJ Hoffmann - Allergy, 2021 - Wiley Online Library
The basophil activation test (BAT) is a functional assay that measures the degree of
degranulation following stimulation with allergen or controls by flow cytometry. It correlates …

The basophil activation test for clinical management of food allergies: recent advances and future directions

D Briceno Noriega, M Teodorowicz… - Journal of Asthma …, 2021 - Taylor & Francis
The basophil activation test (BAT) is an ex vivo functional assay that measures by flow
cytometry the degree of basophil degranulation after stimulation with an allergen. In recent …

Basophil activation test: old and new applications in allergy

O Hemmings, M Kwok, R McKendry… - Current allergy and asthma …, 2018 - Springer
Abstract Purpose of Review The basophil activation test (BAT) using flow cytometry has
supplanted traditional methods of measuring basophil degranulation using histamine and …

Basophil activation testing in diagnosis and monitoring of allergic disease–an overview

B Eberlein, AF Santos, C Mayorga, A Nopp… - Allergo Journal …, 2016 - Springer
The nature of basophil activation as an ex vivo challenge makes it a multifaceted and
promising tool for the allergist. Through the development of flow cytometry, discovery of …

Human basophil activation measured by CD63 expression and LTC4 release in IgE-mediated food allergy

DA Moneret-Vautrin, J Sainte-Laudy, G Kanny… - Annals of Allergy …, 1999 - Elsevier
BACKGROUND: IgE-dependent basophil activation induced by an allergen elicit the release
of LTC4 and the expression of the CD63 membrane marker. OBJECTIVE: The aim of this …