Recent insights into the role of the autonomic nervous system in the creation of substrate for atrial fibrillation: implications for therapies targeting the atrial autonomic …
R Arora - Circulation: Arrhythmia and Electrophysiology, 2012 - Am Heart Assoc
In this review, we discuss recent developments in our understanding of the role of the
autonomic nervous system in creating atrial fibrillation (AF) substrate and on how these …
autonomic nervous system in creating atrial fibrillation (AF) substrate and on how these …
Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation
Background—Electrical, structural, and Ca2+-handling remodeling contribute to the
perpetuation/progression of atrial fibrillation (AF). Recent evidence has suggested a role for …
perpetuation/progression of atrial fibrillation (AF). Recent evidence has suggested a role for …
Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation
Rhythmic and effective cardiac contraction depends on appropriately timed generation and
spread of cardiac electrical activity. The basic cellular unit of such activity is the action …
spread of cardiac electrical activity. The basic cellular unit of such activity is the action …
Antiarrhythmic therapy in atrial fibrillation
U Ravens - Pharmacology & therapeutics, 2010 - Elsevier
Currently available antiarrhythmic drugs for the management of AF are not sufficiently
effective and are burdened with cardiac and extracardiac side effects that may offset their …
effective and are burdened with cardiac and extracardiac side effects that may offset their …
[HTML][HTML] Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior
Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
[HTML][HTML] Remodeling in persistent atrial fibrillation: pathophysiology and therapeutic targets—a systematic review
A Roka, I Burright - Physiologia, 2023 - mdpi.com
Atrial fibrillation (AF) is characterized by disorganized rapid atrial electrical activity, which
leads to impaired atrial function, adverse hemodynamic effects, and increased …
leads to impaired atrial function, adverse hemodynamic effects, and increased …
Distinct patterns of atrial electrical and structural remodeling in angiotensin II mediated atrial fibrillation
HJ Jansen, M Mackasey, M Moghtadaei… - Journal of molecular and …, 2018 - Elsevier
Atrial fibrillation (AF) is prevalent in hypertension and elevated angiotensin II (Ang II);
however, the mechanisms by which Ang II leads to AF are poorly understood. Here, we …
however, the mechanisms by which Ang II leads to AF are poorly understood. Here, we …
Genetic susceptibility to atrial fibrillation is associated with atrial electrical remodeling and adverse post-ablation outcome
Objectives This study sought to assess the atrial electrophysiological properties and post-
ablation outcomes in patients with atrial fibrillation (AF) with and without the rs2200733 …
ablation outcomes in patients with atrial fibrillation (AF) with and without the rs2200733 …
Role of endo-epicardial dissociation of electrical activity and transmural conduction in the development of persistent atrial fibrillation
S Verheule, J Eckstein, D Linz, B Maesen… - Progress in biophysics …, 2014 - Elsevier
Atrial fibrillation (AF) is an arrhythmia that occurs as a result of numerous pathophysiological
processes in the atria. High rate, neurohumoral activation, aging and chronic stretch activate …
processes in the atria. High rate, neurohumoral activation, aging and chronic stretch activate …
[HTML][HTML] The association between diabetes mellitus and atrial fibrillation: clinical and mechanistic insights
A number of clinical studies have reported that diabetes mellitus (DM) is an independent risk
factor for Atrial fibrillation (AF). After adjustment for other known risk factors including age …
factor for Atrial fibrillation (AF). After adjustment for other known risk factors including age …