Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host–virus interaction, and proposed neurotropic mechanisms

AM Baig, A Khaleeq, U Ali, H Syeda - ACS chemical neuroscience, 2020 - ACS Publications
The recent outbreak of coronavirus infectious disease 2019 (COVID-19) has gripped the
world with apprehension and has evoked a scare of epic proportion regarding its potential to …

SARS-CoV-2, more than a respiratory virus: its potential role in neuropathogenesis

CMS Singal, P Jaiswal, P Seth - ACS chemical neuroscience, 2020 - ACS Publications
The coronavirus disease-19 (COVID-19) pandemic has emerged as one of the major
outbreaks to be mentioned in history in coming times. Like severe acute respiratory …

Central nervous system targets and routes for SARS-CoV-2: current views and new hypotheses

FJ Barrantes - ACS chemical neuroscience, 2020 - ACS Publications
As the coronavirus disease 2019 (COVID-19) pandemic unfolds, neurological signs and
symptoms reflect the involvement of targets beyond the primary lung effects. The etiological …

Neurological insights of COVID-19 pandemic

G Das, N Mukherjee, S Ghosh - ACS chemical neuroscience, 2020 - ACS Publications
The novel coronavirus SARS-CoV-2, which was identified after a recent outbreak in Wuhan,
China, in December 2019, has kept the whole world in tenterhooks due to its severe life …

Does COVID19 infect the brain? If so, smokers might be at a higher risk

N Kabbani, JL Olds - Molecular pharmacology, 2020 - ASPET
COVID19 is a devastating global pandemic with epicenters in China, Italy, Spain, and now
the United States. While the majority of infected cases appear mild, in some cases …

Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus …

SARS-CoV-2 infectivity and neurological targets in the brain

WJ Lukiw, A Pogue, JM Hill - Cellular and molecular neurobiology, 2022 - Springer
The gateway for invasion by the novel severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) into human host cells is via the angiotensin-converting enzyme 2 (ACE2) …

Neuroinvasion of SARS-CoV-2 in human and mouse brain

E Song, C Zhang, B Israelow, A Lu-Culligan… - Journal of Experimental …, 2021 - rupress.org
Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects
multiple organ systems including the central nervous system (CNS). Yet, there is no …

Updates on what ACS reported: emerging evidences of COVID-19 with nervous system involvement

AM Baig - ACS chemical neuroscience, 2020 - ACS Publications
With the ongoing pandemic of coronavirus disease (COVID-19) caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), our knowledge of the pathogenesis of …

Understanding the neurotropic characteristics of SARS-CoV-2: from neurological manifestations of COVID-19 to potential neurotropic mechanisms

Z Zhou, H Kang, S Li, X Zhao - Journal of neurology, 2020 - Springer
Abstract Coronavirus disease 2019 (COVID-19), a disease caused by the novel
betacoronavirus (SARS-CoV-2), has become a global pandemic threat. The potential …