Efficacy and safety of dry powder fluticasone propionate in children with persistent asthma

CF LaForce, DS Pearlman, ME Ruff, WS Silvers… - Annals of Allergy …, 2000 - Elsevier
BACKGROUND: Flovent Diskus is a powder formulation of the inhaled corticosteroid
fluticasone propionate (FP) delivered via a breath-actuated, multidose inhaler. OBJECTIVE …

Formoterol Delivered via a New Multi-Dose Dry Powder Inhaler (Certihaler) Is as Effective and Well Tolerated as the Formoterol Dry Powder Inhaler (Aerolizer®) in …

AG Chuchalin, AI Manjra, NN Rozinova… - Journal of aerosol …, 2005 - liebertpub.com
The Certihaler™ is a new multi-dose dry powder inhaler for the delivery of formoterol
(Foradil®), a long-acting β2-agonist. This dose-ranging study compared the efficacy and …

A dose-response study examining the use of methacholine challenge to demonstrate local therapeutic equivalence of the salmeterol component of generic inhaled …

R Allan, S Haughie, R Ahrens, S Singh… - Journal of Aerosol …, 2019 - liebertpub.com
Background: Asthma is widely treated using inhaled corticosteroid/long-acting beta agonist
(LABA) combinations, for example, fluticasone propionate/salmeterol (FPS) dry powder …

[HTML][HTML] Ease of use of the ELLIPTA dry powder inhaler: data from three randomised controlled trials in patients with asthma

H Svedsater, L Jacques, C Goldfrad… - NPJ Primary Care …, 2014 - nature.com
Maintenance therapies for asthma are typically delivered via handheld inhalers. Poor
adherence to inhaled medications and incorrect inhaler technique are known to adversely …

[HTML][HTML] Wixela inhub: a generic equivalent treatment option for patients with asthma or COPD

JF Donohue, DS Burgoyne, JK Ward, R Allan… - Pulmonary …, 2021 - Springer
Purpose The purpose of this review is to discuss the development of Wixela™ Inhub™, a
generic equivalent of Advair Diskus®, a fixed-dose combination of fluticasone …

Patient perceptions of an inhaled asthma medication administered as an inhalation powder via the Diskus or as an inhalation aerosol via a metered-dose inhaler

K Sheth, JA Bernstein, WR Lincourt… - Annals of Allergy …, 2003 - Elsevier
OBJECTIVE: To evaluate patient preference, ease of use, and correctness of use of
fluticasone propionate administered as inhalation powder via the Diskus (GlaxoSmithKline …

P149 Fluticasone propionate and fluticasone propionate/salmeterol multidose dry powder inhaler pharmacokinetics in patients with persistent asthma

P Ratner, G Yiu, C Nugent, S Song… - Annals of Allergy, Asthma & …, 2016 - Elsevier
Methods This multicenter, open-label, 4-period crossover, single-dose study
(NCT02437604) randomized patients aged>/= 12 years with persistent asthma to 1 of the …

[HTML][HTML] Approval of generic fluticasone propionate/salmeterol xinafoate dry powder inhalers in the US: a difficult exercise in regulatory science

A Fuglsang - Pharmaceutical Medicine, 2014 - Springer
In 2013, the US FDA published a draft guidance document for the development of generic
dry powder inhalers containing fluticasone propionate and salmeterol xinafoate. This article …

Randomized, double-blind trial evaluating the efficacy and safety of fluticasone propionate and fluticasone propionate/salmeterol delivered via multidose dry powder …

G Raphael, G Yiu, A Sakov, S Liu, C Caracta - Journal of Asthma, 2018 - Taylor & Francis
Objective: To assess the efficacy and safety of fluticasone propionate (Fp) and Fp/salmeterol
(FS) administered via a novel multidose dry powder inhaler (MDPI) that is easy to use …

Dose-ranging study to evaluate the efficacy and safety of four doses of fluticasone propionate/salmeterol multidose dry powder inhaler (FS MDPI) compared with …

J Steinfeld, G Yiu, SD Miller - Journal of Allergy and Clinical …, 2015 - jacionline.org
Methods Multicenter, randomized, double-blind, single-dose, 6-period crossover, dose-
ranging study in subjects aged≥ 12 years with persistent asthma and predose maximum …