Improved exosome isolation methods from non-small lung cancer cells (NC1975) and their characterization using morphological and surface protein biomarker …

EO Mahgoub, GM Abdella - Journal of Cancer Research and Clinical …, 2023 - Springer
This study has demonstrated improved methods for isolating exosomes from non-small lung
cancer cells, which address the problems characterized by exosome morphological and …

[HTML][HTML] Exosomes derived from cancerous and non-cancerous cells regulate the anti-tumor response in the tumor microenvironment

S Bae, J Brumbaugh, B Bonavida - Genes & cancer, 2018 - ncbi.nlm.nih.gov
The tumor microenvironment (TME) is a unique platform of cancer biology that considers the
local cellular environment in which a tumor exists. Increasing evidence points to the TME as …

Phenotypic and proteomic analysis identifies hallmarks of blood circulating extracellular vesicles in NSCLC responders to immune checkpoint inhibitors

D Brocco, P Lanuti, D Pieragostino, MC Cufaro… - Cancers, 2021 - mdpi.com
Simple Summary Purpose of this study was to investigate the prognostic and predictive role
of blood circulating extracellular vesicles (EVs) in patients with advanced non-small cell lung …

[HTML][HTML] Tumor-derived exosomes in colorectal cancer progression and their clinical applications

J Zhou, XL Li, ZR Chen, WJ Chng - Oncotarget, 2017 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) ranks as the third leading cause of cancer mortality in both of men
and women worldwide due to its metastatic properties and resistance to current treatment …

Tumor-derived exosomes (TEX) and their role in immuno-oncology

TL Whiteside, B Diergaarde, CS Hong - International journal of molecular …, 2021 - mdpi.com
Extracellular vesicles (EVs) play a key role in health and disease, including cancer. Tumors
produce a mix of EVs differing in size, cellular origin, biogenesis and molecular content …

The emerging role of plasma exosomes in diagnosis, prognosis and therapies of patients with cancer

TL Whiteside - Contemporary Oncology/Współczesna Onkologia, 2018 - termedia.pl
Exosomes, small (30-150nm) extracellular vesicles of endocytic origin, are present in all
body fluids of cancer patients. Tumor-derived exosomes, TEX, emerge as potentially …

Potential of cancer cell–derived exosomes in clinical application: a review of recent research advances

Y Sun, J Liu - Clinical therapeutics, 2014 - Elsevier
Abstract Background Exosomes are 30-to 100-nm, membrane-bound vesicles that are
released by most types of cells, including tumor cells. Exosomes contain a great variety of …

Exosomes–structure, biogenesis and biological role in non‐small‐cell lung cancer

M Frydrychowicz… - Scandinavian …, 2015 - Wiley Online Library
Many different cells produce and release membraneous microvesicles (MV) or exosomes
into their microenvironment. Exosomes represent a specific subtype of secreted derived …

Plasma exosome levels in non-small-cell lung cancer: Correlation with clinicopathological features and prognostic implications

Q Liu, Y Xiang, S Yuan, W Xie, C Li, Z Hu… - Cancer …, 2018 - content.iospress.com
BACKGROUND: Biomarker studies revealed important clinical significance of exosome for
cancer patients. However, there is currently no consensus on exosome quantification …

[HTML][HTML] Role of tumour derived exosomes in manuring the metastatic niche in patients with lung cancer liver metastasis: Beyond seed soil hypothesis

KA Shah, SS Patel, KP Bhadresha, K Johar SR… - Advances in Cancer …, 2022 - Elsevier
Metastatic lung cancer is often diagnosed at a late stage and is widely known to metastasize
to the liver in the Asian population, but the underlying mechanism still remains unclear …