High pressure enhancement of enzymes: A review
MJ Eisenmenger, JI Reyes-De-Corcuera - Enzyme and microbial …, 2009 - Elsevier
While most current applications of high pressure (HP) are for inactivating deleterious
enzymes, there is evidence that high pressure can induce stabilization and activation of …
enzymes, there is evidence that high pressure can induce stabilization and activation of …
Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes
Enzymes have great potential in bioprocess engineering due to their green and mild
reaction conditions. However, there are challenges to their application, such as enzyme …
reaction conditions. However, there are challenges to their application, such as enzyme …
Application of high hydrostatic pressure for increasing activity and stability of enzymes
VV Mozhaev, R Lange… - Biotechnology and …, 1996 - Wiley Online Library
Elevated hydrostatic pressure has been used to increase catalytic activity and thermal
stability of α‐chymotrypsin (CT). For an anilide substrate, characterized by a negative value …
stability of α‐chymotrypsin (CT). For an anilide substrate, characterized by a negative value …
[HTML][HTML] High-pressure biotechnology in medicine and pharmaceutical science
P Masson, C Tonello, C Balny - Journal of Biomedicine and …, 2001 - ncbi.nlm.nih.gov
High-pressure (HP) biotechnology is an emerging technique initially applied for food
processing and more recently in pharmaceutical and medical sciences. Pressure can …
processing and more recently in pharmaceutical and medical sciences. Pressure can …
New understandings of thermostable and peizostable enzymes
Recent large-scale studies illustrate the importance of electrostatic interactions near the
surface of proteins as a major factor in enhancing thermal stability. Mutagenesis studies …
surface of proteins as a major factor in enhancing thermal stability. Mutagenesis studies …
Exploiting the effects of high hydrostatic pressure in biotechnological applications
VV Mozhaev, K Heremans, J Frank, P Masson… - Trends in …, 1994 - cell.com
In recent years, there has been increasing interest in exploiting the effects of applied
pressure on biological systems. During the past few years, progress in research into the use …
pressure on biological systems. During the past few years, progress in research into the use …
Effects of high pressure on enzymes related to food quality
M Hendrickx, L Ludikhuyze, I Van den Broeck… - Trends in Food Science …, 1998 - Elsevier
High-pressure processing has potential for food preservation purposes because it can
inactivate microorganisms and enzymes. In order to implement this new technology in the …
inactivate microorganisms and enzymes. In order to implement this new technology in the …
Biotechnology under high pressure: applications and implications
A Aertsen, F Meersman, MEG Hendrickx, RF Vogel… - Trends in …, 2009 - cell.com
Pressure is a thermodynamic parameter whose unique effects on biological systems are
increasingly being studied in a growing number of scientific fields. As such, the effects of …
increasingly being studied in a growing number of scientific fields. As such, the effects of …
Pressure stabilization of proteins from extreme thermophiles
DJ Hei, DS Clark - Applied and Environmental Microbiology, 1994 - Am Soc Microbiol
We describe the stabilization by pressure of enzymes, including a hydrogenase from
Methanococcus jannaschii, an extremely thermophilic deep-sea methanogen. This is the …
Methanococcus jannaschii, an extremely thermophilic deep-sea methanogen. This is the …
Engineering enzymes for non-aqueous solvents
FH Arnold - Trends in biotechnology, 1990 - cell.com
Enzymes may be redesigned to permit catalysis in non-aqueous solvents by engineering
their amino acid sequences, thereby altering their physical and chemical properties to suit …
their amino acid sequences, thereby altering their physical and chemical properties to suit …