The DNA G-quadruplex (GQ) displays structural polymorphisms, and interactions between
its loops and flanking sequences critically determine which of the diverse GQ conformers is …

The lengths of G-tracts and their connecting loop sequences determine G-quadruplex
folding and stability. Complete understanding of the sequence–structure relationships …

Abstract G-quadruplexes (G4s) are non-canonical nucleic acid structures that fold through
complex processes. Characterization of the G4 folding landscape may help to elucidate …

A systematic study on guanine (G) quadruplex DNA flexibility was performed by using
extended explicit molecular dynamics (MD) simulations on four quadruplex molecules …

We have carried out a set of explicit solvent molecular dynamics (MD) simulations on two
DNA quadruplex (G-DNA) molecules, namely the antiparallel d (G4T4G4) 2 dimeric …

Guanine quadruplex (GQ) is a noncanonical nucleic acid structure formed by guanine-rich
DNA and RNA sequences. Folding of GQs is a complex process, where several aspects …

G-quadruplexes (GQs) are key noncanonical DNA and RNA architectures stabilized by
desolvated monovalent cations present in their central channels. We analyze extended …

G-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid
sequences and shown to exist in living cells where they participate in regulation of gene …

Conspectus G-quadruplexes (G4s) are distinctive four-stranded DNA or RNA structures
found within cells that are thought to play functional roles in gene regulation and …

G-quadruplexes (GQs) are four-stranded noncanonical DNA and RNA architectures that can
be formed by guanine-rich sequences. The stability of GQs increases with the number of G …