Therapeutic opportunities in Alzheimer disease: one for all or all for one?
MW Marlatt, KM Webber, PI Moreira… - Current medicinal …, 2005 - ingentaconnect.com
In recent years, Alzheimer disease (AD) has received great attention as an incurable and
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …
Current and emerging therapies for Alzheimer's disease
HB Nygaard - Clinical therapeutics, 2013 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …
Therapeutic perspectives in Alzheimer's disease
JA Tschape, T Hartmann - Recent Patents on CNS Drug …, 2006 - ingentaconnect.com
It is now almost a century ago that Alois Alzheimer first presented his results in public. Main
characteristics of Alzheimer's disease (AD) are massive cerebral accumulation of amyloid …
characteristics of Alzheimer's disease (AD) are massive cerebral accumulation of amyloid …
[HTML][HTML] Advances in developing novel therapeutic strategies for Alzheimer's disease
J Cao, J Hou, J Ping, D Cai - Molecular neurodegeneration, 2018 - Springer
Abstract Alzheimer's Disease (AD), the most prevalent neurodegenerative disease of aging,
affects one in eight older Americans. Nearly all drug treatments tested for AD today have …
affects one in eight older Americans. Nearly all drug treatments tested for AD today have …
Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: a long-range point of view beyond 2020
Recent advances in understanding the molecular mechanisms underlying various paths
toward the pathogenesis of Alzheimer's disease (AD) has begun to provide new insight for …
toward the pathogenesis of Alzheimer's disease (AD) has begun to provide new insight for …
[HTML][HTML] Dreaming of a new world where Alzheimer's is a treatable disorder
Alzheimer's disease (AD) is the most common form of dementia. It'sa chronic and
untreatable neurodegenerative disease with irreversible progression and has important …
untreatable neurodegenerative disease with irreversible progression and has important …
[PDF][PDF] The news advances on Alzheimer's disease's therapeutics.
HQ Sun, X Zhang, WJ Huang… - European Review for …, 2016 - europeanreview.org
Alzheimer's disease (AD) is a multifaceted disorder, characterized by the failure of memory
and dementia. AD affects mostly elder above 65 years of age and is confirmed by post …
and dementia. AD affects mostly elder above 65 years of age and is confirmed by post …
[HTML][HTML] Successful therapies for Alzheimer's disease: why so many in animal models and none in humans?
R Franco, A Cedazo-Minguez - Frontiers in pharmacology, 2014 - frontiersin.org
Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the
therapeutic strategies tested (in animal models) have been successful. One also may notice …
therapeutic strategies tested (in animal models) have been successful. One also may notice …
Overcoming translational barriers impeding development of Alzheimer's disease modifying therapies
TE Golde - Journal of neurochemistry, 2016 - Wiley Online Library
It has now been~ 30 years since the Alzheimer's disease (AD) research entered what may
be termed the 'molecular era'that began with the identification of the amyloid β protein (Aβ) …
be termed the 'molecular era'that began with the identification of the amyloid β protein (Aβ) …
Drug development status for Alzheimer's disease: present scenario
S Misra, B Medhi - Neurological Sciences, 2013 - Springer
Recent advances in the understanding of Alzheimer's disease pathogenesis have led to the
development of numerous compounds that might ameliorate the disease process. Research …
development of numerous compounds that might ameliorate the disease process. Research …