Background: Renal ischemia followed by reperfusion leads to acute renal failure in both
native kidneys and renal allograft. This study aimed at investigating the effects …

BACKGROUND: Ischemia followed by reperfusion leads to acute renal failure in both native
kidneys and a renal allograft. Our previous study found that transplantation of mesenchymal …

Background aims. Ischemia-reperfusion (IR) injury is a common cause of acute renal failure.
Bone marrow (BM)-derived mesenchymal stromal cells (MSC) delivered after renal IR are …

Introduction Studies have shown that stem cells exert their therapeutic effects on acute
kidney injury (AKI) through paracrine/endocrine actions. If the protective effect is mediated in …

BACKGROUND: Ischemia and reperfusion injury (I/R) is the major cause of acute renal
failure (ARF) with high mortality rates. Because alternative therapies are needed, we …

Backgrounds Despite the potential therapeutic benefits, cell therapy in renal ischemia-
reperfusion (I/R) injury is currently limited by low rates of cell engraftment after systemic …

Background: Interest has recently been focused on the possible role of bone marrow-
originating stem cells and the therapeutic role of erythropoietin in the recovery of ischemia …

Acute renal failure (ARF) is a syndrome of abrupt decline in renal function induced by a
number of different insults. In clinic, the common etiology for ARF is ischemia-reperfusion …

Background Reactive oxygen species are important mediators exerting toxic effects on
various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose …

Mesenchymal stromal cells (MSC) have been demonstrated to attenuate renal
ischemia/reperfusion (I/R) damage in rodent models. The mechanisms of such nephro …