[HTML][HTML] Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death
JL Armstrong, DS Hill, CS McKee… - Journal of Investigative …, 2015 - Elsevier
Although the global incidence of cutaneous melanoma is increasing, survival rates for
patients with metastatic disease remain< 10%. Novel treatment strategies are therefore …
patients with metastatic disease remain< 10%. Novel treatment strategies are therefore …
[HTML][HTML] Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
M Salazar, A Carracedo, ÍJ Salanueva… - The Journal of …, 2009 - Am Soc Clin Investig
Autophagy can promote cell survival or cell death, but the molecular basis underlying its
dual role in cancer remains obscure. Here we demonstrate that Δ 9-tetrahydrocannabinol …
dual role in cancer remains obscure. Here we demonstrate that Δ 9-tetrahydrocannabinol …
[HTML][HTML] Molecular mechanism of autophagy and its regulation by cannabinoids in cancer
XC Lee, E Werner, M Falasca - Cancers, 2021 - mdpi.com
Simple Summary This review examines the complex function of autophagy in malignancy
and explores its regulation by cannabinoids in different cancers. Autophagy is an important …
and explores its regulation by cannabinoids in different cancers. Autophagy is an important …
[HTML][HTML] Cannabinoid-associated cell death mechanisms in tumor models
G Calvaruso, O Pellerito… - … journal of oncology, 2012 - spandidos-publications.com
In recent years, cannabinoids (the active components of Cannabis sativa) and their
derivatives have received considerable interest due to findings that they can affect the …
derivatives have received considerable interest due to findings that they can affect the …
[HTML][HTML] Roles of cannabinoids in melanoma: Evidence from in vivo studies
Melanoma is the fourth most common type of cancer diagnosed in Australians after breast,
prostate, and colorectal cancers. While there has been substantial progress in the treatment …
prostate, and colorectal cancers. While there has been substantial progress in the treatment …
Critical appraisal of the potential use of cannabinoids in cancer management
BJ Cridge, RJ Rosengren - Cancer management and research, 2013 - Taylor & Francis
Cannabinoids have been attracting a great deal of interest as potential anticancer agents.
Originally derived from the plant Cannabis sativa, there are now a number of endo-, phyto …
Originally derived from the plant Cannabis sativa, there are now a number of endo-, phyto …
Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy
A Shrivastava, PM Kuzontkoski, JE Groopman… - Molecular cancer …, 2011 - AACR
Cannabidiol (CBD), a major nonpsychoactive constituent of cannabis, is considered an
antineoplastic agent on the basis of its in vitro and in vivo activity against tumor cells …
antineoplastic agent on the basis of its in vitro and in vivo activity against tumor cells …
Cannabinoid receptors as novel targets for the treatment of melanoma
C Blázquez, A Carracedo, L Barrado… - The FASEB …, 2006 - Wiley Online Library
Melanoma causes the greatest number of skin cancer‐related deaths worldwide. Despite
intensive research, prevention and early detection are the only effective measures against …
intensive research, prevention and early detection are the only effective measures against …
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib
ML Goodall, T Wang, KR Martin, MG Kortus… - Autophagy, 2014 - Taylor & Francis
Autophagy is a dynamic cell survival mechanism by which a double-membrane vesicle, or
autophagosome, sequesters portions of the cytosol for delivery to the lysosome for recycling …
autophagosome, sequesters portions of the cytosol for delivery to the lysosome for recycling …
[HTML][HTML] The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action
L Hamtiaux, J Masquelier, GG Muccioli, C Bouzin… - BMC cancer, 2012 - Springer
Background The incidence of melanoma is considerably increasing worldwide. Frequent
failing of classical treatments led to development of novel therapeutic strategies aiming at …
failing of classical treatments led to development of novel therapeutic strategies aiming at …
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- cytotoxic autophagy cell death
- apoptosis and autophagy cell death
- cannabinoid action cell death
- cell death mechanisms
- programmed cell death
- melanoma tumor cells
- synthetic cannabinoids glioblastoma cells
- faah inhibitor melanoma growth
- braf v600e autophagy inhibitors
- tumor suppressors glioblastoma cells
- cannabinoid action glioma cells