Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis

A Salminen, UK Gursoy, S Paju… - Journal of clinical …, 2014 - Wiley Online Library
Aim Chronic periodontitis has an episodic and multifactorial character, with fluctuations in
bacterial burden, inflammatory response, and tissue destruction. We investigated the …

Treatment of periodontitis reduces systemic inflammation in type 2 diabetes

PM Preshaw, JJ Taylor, KM Jaedicke… - Journal of clinical …, 2020 - Wiley Online Library
Aims To assess the impact of periodontal treatment on systemic inflammation in type 2
diabetes. Materials and Methods Adults with type 2 diabetes (n= 83) and without diabetes …

Detection of periodontopathic bacteria and an oxidative stress marker in saliva from periodontitis patients

Y Sawamoto, N Sugano, H Tanaka… - Oral Microbiology and …, 2005 - Wiley Online Library
We assessed the salivary levels of periodontopathic bacteria and 8‐
hydroxydeoxyguanosine (8‐OHdG) in patients with periodontitis. The salivary levels of …

Association and comparison of periodontal and oral hygiene status with serum HbA1c levels: a cross-sectional study

A Rahim, S Hassan, N Ullah, N Noor, Ahmed… - BMC Oral Health, 2023 - Springer
Abstract Background Diabetes Mellitus and periodontitis are chronic diseases with known
reciprocal association. Studies have shown that uncontrolled diabetes increases the risk of …

Salivary lipid peroxidation in patients with generalized chronic periodontitis and acute coronary syndrome

TT Nguyen, LQ Ngo, A Promsudthi… - Journal of …, 2016 - Wiley Online Library
Background: Lipid peroxidation is a major consequence of oxidative stress and can be
evaluated via malondialdehyde (MDA) levels. The present study aims to assess MDA levels …

Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case–control study

L Nibali, F D'Aiuto, G Griffiths, K Patel… - Journal of clinical …, 2007 - Wiley Online Library
Background and Aim: A cluster of metabolic factors defines a syndrome that predisposes to
diabetes and cardiovascular disease. Chronic infections such as periodontitis might alter …

Parameters of oxidative stress in saliva from patients with aggressive and chronic periodontitis

AB Acquier, AK De Couto Pita, L Busch… - Redox …, 2017 - Taylor & Francis
Objectives: Free radicals play an important role in the onset and progression of many
diseases. The aim of this study was to investigate the contribution of oxidative stress in the …

Cigarette smoking aggravates the activity of periodontal disease by disrupting redox homeostasis-an observational study

CH Chang, ML Han, NC Teng, CY Lee, WT Huang… - Scientific reports, 2018 - nature.com
The aim of this study was to evaluate the associations between cigarette use and five
salivary oxidative stress biomarkers, copper-zinc superoxide dismutase (Cu/Zn SOD) …

Malondialdehyde, superoxide dismutase and melatonin levels in gingival crevicular fluid of aggressive and chronic periodontitis patients

NA Ghallab, E Hamdy, OG Shaker - Australian Dental Journal, 2016 - Wiley Online Library
Background The aim of this study was to investigate malondialdehyde (MDA), superoxide
dismutase (SOD) and melatonin levels in the gingival crevicular fluid (GCF) of patients with …

Are inflamed periodontal tissues endogenous source of advanced glycation end-products (AGEs) in individuals with and without diabetes mellitus? A systematic …

A Chopra, TN Jayasinghe, J Eberhard - Biomolecules, 2022 - mdpi.com
Advanced glycation end-products (AGEs) are heterogeneous compounds formed when
excess sugars condense with the amino groups of nucleic acids and proteins. Increased …