The Niemann Pick C1 (NPC1) protein is an intracellular cholesterol transporter located in
the late endosome/lysosome (LE/Ly) and is involved in cholesterol mobilization. Loss-of …

Abstract Niemann-Pick type C1 (NPC1) receptor is an endosomal membrane protein that
regulates intracellular cholesterol trafficking, which is crucial in the Ebola virus (EBOV) cycle …

The entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into human
embryonic kidney (HEK293T) cells has been shown to be a cholesterol-rich, lipid raft …

Abstract Niemann-Pick type C1 (NPC1) receptor is an endosomal membrane protein that
regulates intracellular cholesterol traffic. This protein has been shown to play an important …

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus (SARS-CoV)-2 has resulted in the death of more than 328,000 …

The COVID-19 plague is hitting mankind. Several viruses, including SARS-CoV-1, MERS-
CoV, EBOV, and SARS-CoV-2, use the endocytic machinery to enter the cell. Genomic …

Viruses utilize cellular lipids and manipulate host lipid metabolism to ensure their replication
and spread. Therefore, the identification of lipids and metabolic pathways that are suitable …

The current justified furor regarding epidemic preparedness has emphasized an unmet
need for therapeutic strategies that lead to rapid implementation. The prompt identification …

Coronavirus disease 2019 is a kind of viral pneumonia caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). However, the mechanism whereby SARS-CoV-2 …

SARS‐CoV‐2 is an enveloped positive‐sense RNA virus that depends on host factors for all
stages of its life. Membrane receptor ACE2 is a well‐established factor for SARS‐CoV‐2 …