Repurposing is one of the key opportunities to address the unmet rare diseases therapeutic
need. Based on cases of drug repurposing in small population conditions, and previous …

Currently, there are about 7000 identified rare diseases, together affecting 10% of the
population. However, fewer than 6% of all rare diseases have an approved treatment option …

While nearly 8000 rare diseases have been identified, only 5 percent have licensed
treatments. As most of these diseases are life threatening, it underscores the urgent need for …

There are different approaches to drug repurposing (DR) depending on the status of the
repurposable drug/molecule (approved, investigational, withdrawn, shelved), the context …

Some rare disease treatments come from drug repurposing. The biopharma industry focuses
on commercial rare disease drug repurposing, and disease-specific non-profits and …

Drug repurposing represents a real opportunity to address unmet needs and improve the
lives of rare disease patients. It is often presented as a faster, safer and cheaper path for …

Highlights•Drug repurposing gained momentum in the recent past.•Drug repurposing is a
promising strategy for rare disease drug discovery.•Drug repurposing resulted in fruitful …

IRDiRC Drug Repurposing Guidebook: making better use of existing drugs to tackle rare
diseases Skip to main content Thank you for visiting nature.com. You are using a browser …

Background: The European Commission highlights in its Pharmaceutical Strategy the role of
academic researchers in drug repurposing, especially in the development of orphan …

Repurposing is an increasingly attractive method within the field of drug development for its
efficiency at identifying new therapeutic opportunities among approved drugs at greatly …