Although the early growth response-2 (Egr-2, alias Krox20) protein shows structural and
functional similarities to Egr-1, these two related early-immediate transcription factors are …

Egr-1 (early-growth response factor-1) is a sequence-specific transcription factor that plays a
regulatory role in the expression of many genes important for cell growth, development and …

The ternary complex factors (TCF) are a subfamily of ETS domain transcription factors that
bind and activate serum response elements (SREs) in the promoters of target genes in a …

The extracellular signal-regulated kinase (ERK) pathway leads to activation of the effector
molecule ERK, which controls downstream responses by phosphorylating a variety of …

Early growth response 1 (EGR1) is a multifunctional mammalian transcription factor capable
of both enhancing and/or inhibiting gene expression. EGR1 can be activated by a wide array …

Background Human early growth response-1 (EGR1) is a member of the zing-finger family of
transcription factors induced by a range of molecular and environmental stimuli including …

Transcript elongation by polymerase II paused at the Egr1 promoter is activated by mitogen-
activated protein kinase phosphorylation of the ternary complex factor (TCF) ELK1 bound at …

The early growth response gene 1, EGR1, is an important transcriptional regulator and acts
as the convergent point between a variety of extracellular stimuli and activation of target …

Abstract Background Serum Response Factor (SRF) is a transcription factor that is required
for the expression of many genes including immediate early genes, cytoskeletal genes, and …

The ternary complex factor (TCF) Elk-1 is a transcription factor that regulates immediate
early gene (IEG) expression via the serum response element (SRE) DNA consensus site …