The ability to reprogram somatic cells into induced pluripotent stem cells (iPSCs) using
defined factors provides new tools for biomedical research. However, some iPSC clones …

Direct reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) provides an
invaluable resource for regenerative medicine, enabling the generation of patient-specific …

Summary iPSC technology provides unprecedented opportunities in biomedical research
and regenerative medicine. However, there remain a great deal to learn about iPSC safety …

Stem cells are classified into embryonic stem cells and adult stem cells. An evolving
alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs) …

The discovery of the ability to induce somatic cells to a pluripotent state through the
overexpression of specific transcription factors has the potential to transform the ways in …

Derivation of autologous induced pluripotent stem cells (iPSCs) through direct
reprogramming of easily accessible somatic cells holds the potential to transform the field of …

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was
heralded as a major breakthrough of the decade in stem cell research. The ability to …

Human pluripotent stem cells hold great promise for basic research and regenerative
medicine due to their inherent property to propagate infinitely, while maintaining the …

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by retroviral
overexpression of the transcription factors Oct4, Sox2, Klf4, and c‐Myc holds great promise …

Induced pluripotent stem cells (iPSCs) hold great promise for autologous cell therapies, but
significant roadblocks remain to translating iPSCs to the bedside. For example, concerns …