Acute hyperglycemia and oxidative stress: direct cause and effect?

SW Choi, IFF Benzie, SW Ma, JJ Strain… - Free Radical Biology and …, 2008 - Elsevier
Oxidative stress is increased in Type 2 diabetes and this appears to underlie the
development of diabetic complications. Increased oxidative stress is claimed to be triggered …

Acute hyperglycaemia and oxidative stress generation

A Ceriello - Diabetic medicine, 1997 - Wiley Online Library
Oxidative stress is an acknowledged pathogenic mechanism in diabetic complications.
Several studies have demonstrated that acute hyperglycaemia can impair the physiological …

Oxidative stress in diabetes mellitus: is there a role for hypoglycemic drugs and/or antioxidants

OO Erejuwa - Oxidative stress and diseases, 2012 - books.google.com
The most recent statistics indicate that the global prevalence of diabetes mellitus, estimated
as 366 million in 2011, will increase to 522 million by 2030 (Whiting et al., 2011). Diabetes …

Oxidative stress and glycemic regulation

A Ceriello - Metabolism, 2000 - Elsevier
Oxidative stress is an acknowledged pathogenetic mechanism in diabetic complications.
Hyperglycemia is a widely known cause of enhanced free radical concentration, whereas …

[引用][C] Oxidative stress and insulin action: is there a relationship?

G Paolisso, D Giugliano - Diabetologia, 1996 - Springer
Free radicals are highly reactive atoms or molecules that have one or more unpaired
electrons in their atomic structure. Oxidative damage inflicted by reactive oxygen species is …

Radicals and oxidative stress in diabetes

IC West - Diabetic medicine, 2000 - Wiley Online Library
Recent evidence is reviewed indicating increased oxidative damage in Type 1 and Type 2
diabetes mellitus as well as deficits in antioxidant defence enzymes and vitamins …

Acute and chronic fluctuations in blood glucose levels can increase oxidative stress in type 2 diabetes mellitus

CM Chang, CJ Hsieh, JC Huang, IC Huang - Acta diabetologica, 2012 - Springer
In order to investigate whether short-or long-term glycemic fluctuations could induce
oxidative stress and chronic inflammation, we evaluated the relationships between glycemic …

The possible role of postprandial hyperglycaemia in the pathogenesis of diabetic complications

A Ceriello - Diabetologia, 2003 - Springer
It is both common and wise practice to adjust the treatment of diabetic patients to obtain
plasma glucose concentrations as close as possible to the'normal range', correcting both …

Diabetes, oxidative stress, and antioxidants: a review

AC Maritim, RA Sanders… - Journal of biochemical …, 2003 - Wiley Online Library
Increasing evidence in both experimental and clinical studies suggests that oxidative stress
plays a major role in the pathogenesis of both types of diabetes mellitus. Free radicals are …

[HTML][HTML] Oxidative stress and inflammation in hyperglycemic crises and resolution with insulin: implications for the acute and chronic complications of hyperglycemia

A Chaudhuri, GE Umpierrez - Journal of Diabetes and its …, 2012 - ncbi.nlm.nih.gov
Diabetic ketoacidosis (DKA) is a complex metabolic disorder caused by an absolute or
relative insulin deficiency characterized by hyperglycemia as the result of increased hepatic …